Epinephrine and phenylephrine pretreatments for preventing postreperfusion syndrome during adult liver transplantation

Ho‐Geol Ryu, Chul‐Woo Jung, Hyung‐Chul Lee, Youn‐Joung Cho – 23 July 2012 – Acute hypotension after reperfusion of the liver graft occurs frequently during liver transplantation. A randomized, prospective trial was performed to test the effects of epinephrine and phenylephrine pretreatments for attenuating postreperfusion syndrome (PRS). Ninety‐three adult liver recipients were randomly allocated to receive an intravenous bolus of 10 μg of epinephrine, 100 μg of phenylephrine, or normal saline (the control group) at the time of graft reperfusion.

A randomized controlled trial of pretransplant antiviral therapy to prevent recurrence of hepatitis C after liver transplantation

Gregory T. Everson, Norah A. Terrault, Anna S. Lok, Del R. Rodrigo, Robert S. Brown, Sammy Saab, Mitchell L. Shiffman, Abdullah M.S. Al‐Osaimi, Laura M. Kulik, Brenda W. Gillespie, James E. Everhart, and the Adult‐to‐Adult Living Donor Liver Transplantation Cohort Study – 23 July 2012 – Hepatitis C virus (HCV) infection recurs in liver recipients who are viremic at transplantation. We conducted a randomized, controlled trial to test the efficacy and safety of pretransplant pegylated interferon alpha‐2b plus ribavirin (Peg‐IFN‐α2b/RBV) for prevention of post‐transplant HCV recurrence.

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