Ectopic expression of murine CD47 minimizes macrophage rejection of human hepatocyte xenografts in immunodeficient mice
Johan M. Waern, Qinggong Yuan, Urda Rüdrich, Pablo D. Becker, Kai Schulze, Helene Strick‐Marchand, Nicholas D. Huntington, Behrend J. Zacher, Karsten Wursthorn, James P. DiSanto, Carlos A. Guzman, Michael P. Manns, Michael Ott, Michael Bock – 26 April 2012 – Macrophages play an important role in the rejection of xenogeneic cells and therefore represent a major obstacle to generating chimeric mice with human xenografts that are useful tools for basic and preclinical medical research.