Role of regulatory T cells in the promotion of transplant tolerance

Itay Shalev, Nazia Selzner, Wendy Shyu, David Grant, Gary Levy – 21 April 2012 – Liver transplantation is now recognized as the most effective therapy for patients with end‐stage acute and chronic liver failure. Despite outstanding short‐term graft and patient survival, liver transplantation continues to face several major challenges, including poor long‐term graft survival due to chronic rejection and major side effects of long‐term immunosuppressive therapy (which is required for the prevention of rejection).

Usability of ringed polytetrafluoroethylene grafts for middle hepatic vein reconstruction during living donor liver transplantation

Shin Hwang, Dong‐Hwan Jung, Tae‐Yong Ha, Chul‐Soo Ahn, Deok‐Bog Moon, Ki‐Hun Kim, Gi‐Won Song, Gil‐Chun Park, Sung‐Won Jung, Sam‐Youl Yoon, Jung‐Man Namgoong, Chun‐Soo Park, Yo‐Han Park, Hyeong‐Woo Park, Hyo‐Jun Lee, Sung‐Gyu Lee – 18 April 2012 – Large vein allografts are suitable for middle hepatic vein (MHV) reconstruction, but their supply is often limited. Although polytetrafluoroethylene (PTFE) grafts are unlimitedly available, their long‐term patency is relatively poor.

Two immunogenic passenger dendritic cell subsets in the rat liver have distinct trafficking patterns and radiosensitivities

Bin Yu, Hisashi Ueta, Yusuke Kitazawa, Toshiya Tanaka, Kensuke Adachi, Hiromitsu Kimura, Miwa Morita, Yasushi Sawanobori, Hai Xin Qian, Tatsuhiko Kodama, Kenjiro Matsuno – 18 April 2012 – The aim of this study was to investigate the trafficking patterns, radiation sensitivities, and functions of conventional dendritic cell (DC) subsets in the rat liver in an allotransplantation setting. We examined DCs in the liver, hepatic lymph, and graft tissues and recipient secondary lymphoid organs after liver transplantation from rats treated or untreated by sublethal irradiation.

Subscribe to