Heather Francis – 28 February 2012

Gong‐Hao He, Gui‐Li Xu, Wen‐Ke Cai, Wei Xia – 28 February 2012

Ian A. Rowe, Richard Parker, Matthew J. Armstrong, Diarmaid D. Houlihan, David J. Mutimer – 28 February 2012 – Hepatitis A virus (HAV) superinfection in persons with hepatitis C virus (HCV) infection has been associated with a high mortality rate, and vaccination is recommended. The incidence of HAV is low, and the aim of this study was to determine the mortality risk of HAV superinfection and the consequences of routine vaccination in persons with HCV infection.

Rodrigo Liberal, Charlotte R. Grant, Beth S. Holder, Yun Ma, Giorgina Mieli‐Vergani, Diego Vergani, Maria Serena Longhi – 28 February 2012 – In autoimmune hepatitis (AIH), liver‐damaging CD4 T cell responses are associated with defective CD4posCD25pos regulatory T cells (T‐regs). Galectin‐9 (Gal9), a β‐galactosidase–binding protein expressed by T‐regs, is key to their function, inhibiting T helper 1 immune responses by binding T cell immunoglobulin and mucin domain 3 (Tim‐3) on CD4 effector cells.

Amirfarbod Yazdanyar, Xian‐Cheng Jiang – 24 February 2012 – It is known that plasma phospholipid transfer protein (PLTP) activity influences lipoprotein metabolism. The liver is one of the major sites of lipoprotein production and degradation, as well as of PLTP expression. To address the impact of liver‐expressed PLTP on lipoprotein metabolism, we created a mouse model that expresses PLTP in the liver acutely and specifically, with a PLTP‐null background. This approach in mouse model preparations can also be used universally for evaluating the function of many other genes in the liver.

Michael R. Lucey – 24 February 2012 – Watch the video presentation of this article

Akihide Kamiya, Atsushi Miyajima – 23 February 2012

Chapy Venkatesan, Zobair M. Younossi – 23 February 2012

James D. Perkins – 23 February 2012

Umberto Baccarani, Luigia Scudeller, Gian Luigi Adani, Pierluigi Viale, Marcello Tavio – 23 February 2012