Pierre‐Yves Bochud, Stéphanie Bibert, Zoltán Kutalik, Etienne Patin, Julien Guergnon, Bertrand Nalpas, Nicolas Goossens, Lorenz Kuske, Beat Müllhaupt, Tillman Gerlach, Markus H.
Hiroyoshi Doi, Tara K. Iyer, Erica Carpenter, Hong Li, Kyong‐Mi Chang, Robert H. Vonderheide, David E. Kaplan – 19 September 2011 – Chronic hepatitis C virus (HCV) infection is a leading cause of cirrhosis and hepatocellular carcinoma (HCC). Both advanced solid tumors and HCV have previously been associated with memory B‐cell dysfunction. In this study, we sought to dissect the effect of viral infection, cirrhosis, and liver cancer on memory B‐cell frequency and function in the spectrum of HCV disease.
Fanyin Meng, Heather Francis, Shannon Glaser, Yuyan Han, Sharon DeMorrow, Allison Stokes, Dustin Staloch, Julie Venter, Melanie White, Yoshiyuki Ueno, Lola M. Reid, Gianfranco Alpini – 19 September 2011 – Functional pluripotent characteristics have been observed in specific subpopulations of hepatic cells that express some of the known cholangiocyte markers.
Chao Wang, Wen Yang, He‐Xin Yan, Tao Luo, Jian Zhang, Liang Tang, Fu‐Quan Wu, Hui‐Lu Zhang, Le‐Xing Yu, Long‐Yi Zheng, Yu‐Qiong Li, Wei Dong, Ya‐Qin He, Qiong Liu, Shan‐Shan Zou, Yan Lin, Liang Hu, Zhong Li, Meng‐Chao Wu, Hong‐Yang Wang – 19 September 2011 – Hepatitis B virus X (HBx) protein is implicated in hepatitis B virus (HBV)‐associated liver carcinogenesis. However, it remains unclear whether HBx‐expressing hepatic progenitor cells (HPCs) are attributed to liver tumor formation.
Florie Borel, Ruiqi Han, Allerdien Visser, Harald Petry, Sander J.H. van Deventer, Peter L.M. Jansen, Pavlina Konstantinova, with collaboration of the Réseau Centre de Ressources Biologiques Foie (French Liver Biobanks Network), France – 19 September 2011 – Adenosine triphosphate (ATP)‐binding cassette (ABC) transporters are drug efflux pumps responsible for the multidrug resistance phenotype causing hepatocellular carcinoma (HCC) treatment failure.
Waqar R. R. Farid, Qiuwei Pan, Adriaan J. P. van der Meer, Petra E. de Ruiter, Vedashree Ramakrishnaiah, Jeroen de Jonge, Jaap Kwekkeboom, Harry L. A. Janssen, Herold J. Metselaar, Hugo W. Tilanus, Geert Kazemier, Luc J.W. van der Laan – 19 September 2011 – Recent animal and human studies have highlighted the potential of hepatocyte‐derived microRNAs (HDmiRs) in serum as early, stable, sensitive, and specific biomarkers of liver injury. Their usefulness in human liver transplantation, however, has not been addressed.
Meng Y. Wang, Darryn R. Potosky, Sandeep Khurana – 19 September 2011
Alice Marmugi, Simon Ducheix, Frédéric Lasserre, Arnaud Polizzi, Alain Paris, Nathalie Priymenko, Justine Bertrand‐Michel, Thierry Pineau, Hervé Guillou, Pascal G.P. Martin, Laïla Mselli‐Lakhal – 19 September 2011 – Changes in lifestyle are suspected to have strongly influenced the current obesity epidemic.
Romain Coriat, Olivier Mir, François Goldwasser, Stanislas Pol, Stanislas Chaussade – 19 September 2011
Yoichi Ishizaki, Seiji Kawasaki, Hiroyuki Sugo, Jiro Yoshimoto, Noriko Fujiwara, Hiroshi Imamura – 19 September 2011 – Recently, the successful application of portal inflow modulation has led to renewed interest in the use of left lobe grafts in adult‐to‐adult living donor liver transplantation (LDLT). However, data on the hepatic hemodynamics supporting portal inflow modulation are limited, and the optimal portal circulation for a liver graft is still unclear. We analyzed 42 consecutive adult‐to‐adult left lobe LDLT cases without splenectomy or a portocaval shunt.