Jian Yao, Linhui Liang, Shenglin Huang, Jie Ding, Ning Tan, Yingjun Zhao, Mingxia Yan, Chao Ge, Zhenfeng Zhang, Taoyang Chen, Dafang Wan, Ming Yao, Jinjun Li, Jianren Gu, Xianghuo He – 30 November 2009 – The pathological relevance and significance of microRNAs (miRNAs) in hepatocarcinogenesis have attracted much attention in recent years; however, little is known about the underlying molecular mechanisms through which miRNAs are involved in the development and progression of hepatocellular carcinoma (HCC).

Hao Yin, Linling Cheng, Michael Holt, Numsen Hail, Robert MacLaren, Cynthia Ju – 30 November 2009 – Acetaminophen‐induced liver injury (AILI) is a significant health problem and represents the most frequent cause of drug‐induced liver failure in the United States. The development and implementation of successful therapeutic intervention strategies have been demanding, due to significant limitations associated with the current treatment for AILI. Lactoferrin (Lac), a glycoprotein present in milk, has been demonstrated to possess a multitude of biological functions.

Tsan‐Shiun Lin, Allan M. Concejero, Chao‐Long Chen, Yuan‐Cheng Chiang, Chih‐Chi Wang, Shih‐Ho Wang, Yueh‐Wei Liu, Chin‐Hsiang Yang, Chee‐Chien Yong, Bruno Jawan, Yu‐Fan Cheng – 24 November 2009 – Biliary reconstruction using a microsurgical technique in living donor liver transplantation was routinely performed on 88 grafts primarily transplanted into 85 patients. All procedures were performed under a microscope by a single microsurgeon. Except for biliary atresia and Alagille syndrome, duct‐to‐duct reconstruction was performed. Stents were not used.

Pratima Sharma, Douglas E. Schaubel, Mary K. Guidinger, Robert M. Merion – 24 November 2009 – More candidates with creatinine levels ≥ 2 mg/dL have undergone liver transplantation (LT) since the implementation of Model for End‐Stage Liver Disease (MELD)–based allocation. These candidates have higher posttransplant mortality. This study examined the effect of serum creatinine on survival benefit among candidates undergoing LT. Scientific Registry of Transplant Recipients data were analyzed for adult LT candidates listed between September 2001 and December 2006 (n = 38,899).

Jana Hudcova, Roman Schumann – 24 November 2009

Naim Alkhouri, Christine Carter‐Kent, Shadi Mayacy, Vera Hupertz, Bijan Eghtesad, Cristiano Quintini, John Fung, Kadakkal Radhakrishnan – 24 November 2009

Markus Selzner, Arash Kashfi, Mark S. Cattral, Nazia Selzner, Paul D. Greig, Les Lilly, Ian D. McGilvray, George Therapondos, Lesley E. Adcock, Anand Ghanekar, Gary A. Levy, Eberhard L. Renner, David R. Grant – 24 November 2009 – Many centers require a minimal graft to body weight ratio (GBWR) ≥ 0.8 as an arbitrary threshold to proceed with right‐lobe living donor liver transplantation (RL‐LDLT), and there is often hesitancy about transplanting lower volume living donor (LD) liver grafts into sicker patients.

Shahid M. Malik, Michael E. deVera, Paulo Fontes, Obaid Shaikh, Eizaburo Sasatomi, Jawad Ahmad – 24 November 2009 – Recurrence of the original disease following liver transplantation is not uncommon and can lead to graft failure. There are limited data on recurrent fatty liver disease following liver transplantation. The aim of this study was to determine the incidence of recurrent fatty liver disease in patients with biopsy‐proven nonalcoholic steatohepatitis, its effect on survival, and whether there are any predictive factors for recurrence.

Vishal Bhagat, Ayse L. Mindikoglu, Carmine G. Nudo, Eugene R. Schiff, Andreas Tzakis, Arie Regev – 24 November 2009 – Nonalcoholic steatohepatitis (NASH) is becoming a common cause of liver cirrhosis requiring liver transplantation (LT). Cardiovascular complications related to metabolic syndrome and NASH recurrence in the transplanted liver may affect the outcome of LT in these patients. We compared the outcomes of LT for NASH cirrhosis and alcoholic cirrhosis (ETOH) in a large transplant center.

24 November 2009