Systematic review of randomized trials on vasoconstrictor drugs for hepatorenal syndrome
Lise L. Gluud, Kurt Christensen, Erik Christensen, Aleksander Krag – 25 January 2010 – Vasoconstrictor drugs may improve renal function in hepatorenal syndrome (HRS), but the effect on mortality has not been established. We therefore performed a systematic review of randomized trials on vasoconstrictor drugs for type 1 or type 2 HRS. Mortality was the primary outcome measure. Eligible trials were identified through electronic and manual searches. Intention‐to‐treat random effects meta‐analyses were performed.