Loredana Fiorentino, Alessia Vivanti, Michele Cavalera, Valeria Marzano, Maurizio Ronci, Marta Fabrizi, Stefano Menini, Giuseppe Pugliese, Rossella Menghini, Rama Khokha, Renato Lauro, Andrea Urbani, Massimo Federici – 23 December 2009 – Tumor necrosis factor α–converting enzyme (TACE, also known as ADAM17) was recently involved in the pathogenesis of insulin resistance.
Wagane J. A. Benga, Sophie E. Krieger, Maria Dimitrova, Mirjam B. Zeisel, Marie Parnot, Joachim Lupberger, Eberhard Hildt, Guangxiang Luo, John McLauchlan, Thomas F. Baumert, Catherine Schuster – 23 December 2009 – Chronic hepatitis C virus (HCV) infection is a major cause of liver disease worldwide. Restriction of HCV infection to human hepatocytes suggests that liver‐specific host factors play a role in the viral life cycle.
Apurva A. Modi, Jordan J. Feld, Yoon Park, David E. Kleiner, James E. Everhart, T. Jake Liang, Jay H. Hoofnagle – 23 December 2009 – Although coffee consumption has been associated with reduced frequency of liver disease, it is unclear whether the effect is from coffee or caffeine and whether there is an effect on hepatic fibrosis specifically. This study was undertaken to use a food‐frequency instrument for dietary caffeine consumption to evaluate the relationship between caffeine intake and liver fibrosis.
Karim Si‐Tayeb, Fallon K. Noto, Masato Nagaoka, Jixuan Li, Michele A. Battle, Christine Duris, Paula E. North, Stephen Dalton, Stephen A. Duncan – 23 December 2009 – There exists a worldwide shortage of donor livers available for orthotropic liver transplantation and hepatocyte transplantation therapies.
Naohisa Kuriyama, Shuji Isaji, Takashi Hamada, Masashi Kishiwada, Ichiro Ohsawa, Masanobu Usui, Hiroyuki Sakurai, Masami Tabata, Tatsuya Hayashi, Koji Suzuki – 23 December 2009 – Small‐for‐size liver grafts are a serious obstacle for partial orthotopic liver transplantation. Activated protein C (APC), a potent anticoagulant serine protease, is known to have cell‐protective properties due to its anti‐inflammatory and antiapoptotic activities.
Elizabeth B. Haagsma – 23 December 2009
Leen Delang, Johan Neyts – 23 December 2009
James E. Nelson, Kris V. Kowdley – 23 December 2009
Carla S. Coffin, Abdel Aziz M. Shaheen, Kelly W. Burak, Robert P. Myers – 23 December 2009 – Liver transplant recipients and their infants may have an increased risk of obstetric complications. Our objective was to describe pregnancy outcomes in women with a prior transplant from a population‐based perspective. We analyzed the 1993–2005 US Nationwide Inpatient Sample database to identify obstetric hospitalizations among transplant recipients (n = 206) and controls matched by age, hospital, and year (n = 4060).
Julie Lucifora, David Durantel, Barbara Testoni, Olivier Hantz, Massimo Levrero, Fabien Zoulim – 23 December 2009 – Hepatitis B virus (HBV) is currently viewed as a stealth virus that does not elicit innate immunity in vivo. This assumption has not yet been challenged in vitro because of the lack of a relevant cell culture system. The HepaRG cell line, which is physiologically closer to differentiated hepatocytes and permissive to HBV infection, has opened new perspectives in this respect.HBV baculoviruses were used to initiate an HBV replication in both HepG2 and HepaRG cells.