Aurelie Plessier, Sarwa Darwish‐Murad, Manuel Hernandez‐Guerra, Yann Consigny, Federica Fabris, Jonel Trebicka, Jorg Heller, Isabelle Morard, Luc Lasser, Philippe Langlet, Marie‐Hélène Denninger, Dominique Vidaud, Bertrand Condat, Antoine Hadengue, Massimo Primignani, Juan‐Carlos Garcia‐Pagan, Harry L. A. Janssen, Dominique Valla, European Network for Vascular Disorders of the Liver (EN‐Vie) – 23 December 2009 – Current recommendations for early anticoagulation in acute portal vein thrombosis unrelated to cirrhosis or malignancy are based on limited evidence.

Christoph Neumann‐Haefelin, Jörg Timm, Julia Schmidt, Nadine Kersting, Karen Fitzmaurice, Cesar Oniangue‐Ndza, Michael N. Kemper, Isla Humphreys, Susan McKiernan, Dermot Kelleher, Volker Lohmann, Paul Bowness, Daniela Huzly, Hugo R. Rosen, Arthur Y. Kim, Georg M. Lauer, Todd M. Allen, Eleanor Barnes, Michael Roggendorf, Hubert E. Blum, Robert Thimme – 23 December 2009 – Human leukocyte antigen B27 (HLA‐B27) is associated with protection in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection.

Kathleen E. Corey, Raymond T. Chung – 23 December 2009

Katherine James, Elisa Bertoja, James O'Beirne, Susan Mallett – 23 December 2009 – Budd‐Chiari syndrome (BCS) is the end result of a number of disease states resulting in hepatic venous outflow obstruction. We report a Janus kinase 2–homozygous patient with BCS who thrombosed a transjugular intrahepatic portosystemic shunt (TIPS) despite treatment with warfarin (international normalized ratio = 3.0), aspirin, and clopidogrel.

Darjus F. Tschaharganeh, Michaela Kaldenbach, Stephanie Erschfeld, Jens J. W. Tischendorf, Christian Trautwein, Konrad L. Streetz – 23 December 2009 – Hepatocyte transplantation (HT) is still restricted by the limited amount of transplantable cells. Therefore, a better understanding of the mechanisms involved in cellular engraftment, proliferation, and in vivo selection is important. Here we aimed to evaluate the role of the interleukin 6 (IL‐6)/glycoprotein 130 (gp130) system for liver repopulation.

23 December 2009

23 December 2009

Ana Paula Barreiros, Christian Geber, Frank Birklein, Peter R. Galle, Gerd Otto – 23 December 2009

Pierre Pradat, Eric Trepo, Andrej Potthoff, Rakesh Bakshi, Bradford Young, Christian Trepo, Robert Lagier, Christophe Moreno, Arnaud Lemmers, Thierry Gustot, Delphine Degre, Michael Adler, Heiner Wedemeyer – 23 December 2009

Chieko Saito, Claudia Zwingmann, Hartmut Jaeschke – 23 December 2009 – Acetaminophen (APAP) overdose is a major cause of acute liver failure. The glutathione (GSH) precursor N‐acetylcysteine (NAC) is used to treat patients with APAP overdose for up to 48 hours. Although it is well established that early treatment with NAC can improve the scavenging of the reactive metabolite N‐acetyl‐p‐benzoquinone imine, protective mechanisms at later times remain unclear.