Srinath Chinnakotla, Gary L. Davis, Sugam Vasani, Peter Kim, Koji Tomiyama, Edmund Sanchez, Nicholas Onaca, Robert Goldstein, Marlon Levy, Göran B. Klintmalm – 24 November 2009 – Tumor recurrence after liver transplantation for hepatocellular carcinoma is associated with a poor prognosis. Because immunosuppression is a well‐known risk factor for tumor growth, it is surprising that its possible role in the outcome of liver transplantation has been poorly evaluated.

Mureo Kasahara, Reiko Horikawa, Seisuke Sakamoto, Takanobu Shigeta, Hideaki Tanaka, Akinari Fukuda, Kiyomi Abe, Keisuke Yoshii, Yasuhiro Naiki, Rika Kosaki, Atsuko Nakagawa – 24 November 2009 – Glycogen storage disease type 1b (GSD‐1b) is due to an autosomal recessive inborn error of carbohydrate metabolism caused by defects in glucose‐6‐phosphatase translocase. Patients with GSD‐1b have severe hypoglycemia with several clinical manifestations of hepatomegaly, obesity, a doll‐like face, and neutropenia. Liver transplantation has been indicated for severe glucose intolerance.

Xavier Xiol, Jose Castellote, Xavier Fuentes‐Arderiu – 24 November 2009

Rhiana Garritsen, Andrei Tintu, Herold Metselaar, Geert Kazemier – 24 November 2009

Salvador Benlloch, Laura Heredia, Claudia Barquero, José‐Miguel Rayón, Ramón Pina, Victoria Aguilera, Martín Prieto, Marina Berenguer – 24 November 2009 – We previously developed a mathematical model, the Hospital Universitario La Fe (HULF) index, as an alternative to protocol liver biopsy (PLB) to estimate significant fibrosis (SF) in patients who underwent liver transplantation (LT) for liver damage caused by chronic HCV infection. In the present study, we sought to validate this noninvasive index.

Pinelopi Manousou, Dimitrios Samonakis, Evangelos Cholongitas, David Patch, James O'Beirne, Amar P. Dhillon, Keith Rolles, Aiden McCormick, Peter Hayes, Andrew K. Burroughs – 24 November 2009 – Less potent immunosuppression is considered to reduce the severity of hepatitis C virus (HCV) recurrence after liver transplantation. An optimal regimen is unknown. We evaluated tacrolimus monotherapy versus triple therapy in a randomized trial of 103 first transplants for HCV cirrhosis.

Vandana Singh, Madhavi Rudraraju, Elizabeth J. Carey, Thomas J. Byrne, David D. Douglas, Jorge Rakela, Hugo E. Vargas – 24 November 2009

Thierry Gustot, François Durand, Didier Lebrec, Jean‐Louis Vincent, Richard Moreau – 20 November 2009 – Sepsis is physiologically viewed as a proinflammatory and procoagulant response to invading pathogens. There are three recognized stages in the inflammatory response with progressively increased risk of end‐organ failure and death: sepsis, severe sepsis, and septic shock. Patients with cirrhosis are prone to develop sepsis, sepsis‐induced organ failure, and death.

Fan Wu, Lian‐Yue Yang, Yun‐Feng Li, Di‐Peng Ou, Dong‐Ping Chen, Chun Fan – 20 November 2009 – Epidermal growth factor‐like domain 7 (Egfl7) is a recently identified secreted protein that is believed to be primarily expressed in endothelial cells (ECs). Although its expression was reported elevated during tumorigenesis, whether and how Egfl7 contributes to human malignancies remains unknown. In the present study overexpression of Egfl7 was found predominantly in hepatocellular carcinoma (HCC) cells in HCC tissues and closely correlated with poor prognosis of HCC.

David Durantel, Fabien Zoulim – 20 November 2009