A graft to body weight ratio less than 0.8 does not exclude adult‐to‐adult right‐lobe living donor liver transplantation

Markus Selzner, Arash Kashfi, Mark S. Cattral, Nazia Selzner, Paul D. Greig, Les Lilly, Ian D. McGilvray, George Therapondos, Lesley E. Adcock, Anand Ghanekar, Gary A. Levy, Eberhard L. Renner, David R. Grant – 24 November 2009 – Many centers require a minimal graft to body weight ratio (GBWR) ≥ 0.8 as an arbitrary threshold to proceed with right‐lobe living donor liver transplantation (RL‐LDLT), and there is often hesitancy about transplanting lower volume living donor (LD) liver grafts into sicker patients.

Recurrent disease following liver transplantation for nonalcoholic steatohepatitis cirrhosis

Shahid M. Malik, Michael E. deVera, Paulo Fontes, Obaid Shaikh, Eizaburo Sasatomi, Jawad Ahmad – 24 November 2009 – Recurrence of the original disease following liver transplantation is not uncommon and can lead to graft failure. There are limited data on recurrent fatty liver disease following liver transplantation. The aim of this study was to determine the incidence of recurrent fatty liver disease in patients with biopsy‐proven nonalcoholic steatohepatitis, its effect on survival, and whether there are any predictive factors for recurrence.

Outcomes of liver transplantation in patients with cirrhosis due to nonalcoholic steatohepatitis versus patients with cirrhosis due to alcoholic liver disease

Vishal Bhagat, Ayse L. Mindikoglu, Carmine G. Nudo, Eugene R. Schiff, Andreas Tzakis, Arie Regev – 24 November 2009 – Nonalcoholic steatohepatitis (NASH) is becoming a common cause of liver cirrhosis requiring liver transplantation (LT). Cardiovascular complications related to metabolic syndrome and NASH recurrence in the transplanted liver may affect the outcome of LT in these patients. We compared the outcomes of LT for NASH cirrhosis and alcoholic cirrhosis (ETOH) in a large transplant center.

Natural history of post–liver transplantation hepatitis C: A review of factors that may influence its course

Juan F. Gallegos‐Orozco, Amir Yosephy, Brie Noble, Bashar A. Aqel, Thomas J. Byrne, Elizabeth J. Carey, David D. Douglas, David Mulligan, Adyr Moss, Giovanni de Petris, James W. Williams, Jorge Rakela, Hugo E. Vargas – 24 November 2009 – Our aim was to assess long‐term survival in patients transplanted for HCV‐related end‐stage liver disease (ESLD) and evaluate potentially modifiable predictors of survival. We performed a retrospective analysis of adult liver transplants (LT) at our institution for HCV‐related ESLD since the program's inception.

Living donor liver transplantation for hepatocellular carcinoma: Increased recurrence but improved survival

Khashayar Vakili, James J. Pomposelli, Yee Lee Cheah, Mohamed Akoad, W. David Lewis, Urmila Khettry, Fredric Gordon, Khalid Khwaja, Roger Jenkins, Elizabeth A. Pomfret – 24 November 2009 – In regions with a limited deceased donor pool, living donor adult liver transplantation (LDALT) has become an important treatment modality for patients with hepatocellular carcinoma (HCC) and cirrhosis. Studies have shown higher recurrence rates of HCC after LDALT in comparison with deceased donor liver transplantation (DDLT).

Acute kidney injury during liver transplantation as determined by neutrophil gelatinase‐associated lipocalin

Claus U. Niemann, Ann Walia, Jeffrey Waldman, Michael Davio, John P. Roberts, Ryutaro Hirose, John Feiner – 24 November 2009 – Acute kidney injury (AKI) has significant prognostic implications for long‐term outcomes in patients undergoing liver transplantation. In several retrospective studies, perioperative variables have been associated with AKI. These variables have been mainly associated with changes in creatinine concentrations over several days or months post‐transplantation.

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