Acute hemodynamic response to propranolol predicts bleeding and nonbleeding decompensation in patients with cirrhosis
Benedikt S. Hofer, Benedikt Simbrunner, David J. M. Bauer, Rafael Paternostro, Philipp Schwabl, Bernhard Scheiner, Georg Semmler, Lukas Hartl, Mathias Jachs, Barbara Datterl, Albert F. Staettermayer, Michael Trauner, Mattias Mandorfer, Thomas Reiberger – 7 July 2022 – Nonselective beta‐blockers are used as prophylaxis for variceal bleeding in patients with advanced chronic liver disease (ACLD). The acute hemodynamic response to intravenous propranolol (i.e., ≥10% reduction in hepatic venous pressure gradient [HVPG]) is linked to a decreased risk of variceal bleeding.