Spatial transcriptomics identifies enriched gene expression and cell types in human liver fibrosis
Brian K. Chung, Jonas Øgaard, Henrik Mikael Reims, Tom H. Karlsen, Espen Melum – 19 June 2022 – Liver fibrosis and cirrhosis have limited therapeutic options and represent a serious unmet patient need. Recent use of single‐cell RNA sequencing (scRNAseq) has identified enriched cell types infiltrating cirrhotic livers but without defining the microanatomical location of these lineages thoroughly.