Acute portal hypertension using portal vein ligation abrogates TRAIL expression of liver‐resident NK cells
Yuki Imaoka, Koki Sato, Masahiro Ohira, Kouki Imaoka, Takuya Yano, Ryosuke Nakano, Yuka Tanaka, Hideki Ohdan – 19 June 2022 – The effects of acute portal hypertension (PHT), which is reported as poor prognostic factors in patients with hepatocellular carcinoma, are not well known on the liver immune system, including natural killer (NK) cells. The aim of this study, therefore, was to investigate how acute PHT influences the functions and characteristics of liver‐resident NK (lr‐NK) cells using an acute PHT mouse model.