Chen Hao, Mao Anwei, Chen Bing, Shen Baiyong, Zhang Weixia, Shen Chuan, Chen Erzhen, Deng Xiaxing, Qiu Weihua, Yang Weiping, Peng Chenghong, Li Hongwei – 30 July 2008 – Mycophenolate mofetil (MMF) is a very powerful immunosuppressive drug used in preventing acute rejection in liver transplantation. However, MMF has some serious side effects, including hematologic and gastrointestinal disorders. This study was designed to investigate the relationship between the clinical events and the pharmacokinetics of mycophenolic acid (MPA) in Chinese liver transplant recipients.

P. V. Suneetha, Ingmar Mederacke, Albert Heim, Murat Bastürk, Markus Cornberg, Christian P. Strassburg, Michael P. Manns, Heiner Wedemeyer – 30 July 2008

Kensuke Miyazaki, Mitsuhisa Takatsuki, Susumu Eguchi, Masaaki Hidaka, Hirotaka Tokai, Koji Hamasaki, Yoshitsugu Tajima, Takashi Kanematsu – 30 July 2008

Mariagrazia Tateo, Mylène Sebagh, Marie‐Pierre Bralet, Elina Teicher, Daniel Azoulay, Vincent Mallet, Stanislas Pol, Denis Castaing, Didier Samuel, Jean‐Charles Duclos‐Vallée – 30 July 2008 – Nodular regenerative hyperplasia is one of the causes of noncirrhotic portal hypertension and has recently been described in human immunodeficiency virus–infected patients, and the potential role of a prothrombotic state and hepatotoxic antiretroviral medication has been suggested. Moreover, it is now established that liver transplantation is feasible in HIV‐infected patients.

Constantino Fondevila, Xiu‐Da Shen, Seiichiro Tsuchihashi, Yoichiro Uchida, Maria Cecilia Freitas, Bibo Ke, Ronald W. Busuttil, Jerzy W. Kupiec‐Weglinski – 30 July 2008 – Activation of the complement cascade represents an important event during ischemia/reperfusion injury (IRI). This work was designed to investigate the role of the membrane attack complex (MAC; C5b‐9) in the pathogenesis of hepatic IRI. Livers from B&W/Stahl/rC6(+) and C6(−) rats were harvested, stored for 24 hours at 4°C, and then transplanted [orthotopic liver transplantation (OLT)] to syngeneic recipients.

Loreto Hierro, Ruth Díez‐Dorado, Carmen Díaz, Angela De la Vega, Esteban Frauca, Carmen Camarena, Gema Muñoz‐Bartolo, Ana González de Zárate, Manuel López Santamaría, Paloma Jara – 30 July 2008 – Epstein‐Barr virus (EBV) infection after liver transplantation (LT) is associated with increased risk of posttransplant lymphoproliferative disorder (PTLD). Lowering immunosuppression is the current method to prevent PTLD in LT children with a high viral load. The aim of this study was to assess the efficacy and safety of valganciclovir (VGCV) in children with EBV infection after LT.

Jin Hyoung Kim, Gi‐Young Ko, Kyu‐Bo Sung, Hyun‐Ki Yoon, Dong Il Gwon, Kyung Rae Kim, Sung‐Gyu Lee – 30 July 2008 – Percutaneous transhepatic treatment may be effective in patients with bile leaks after living donor liver transplantation (LDLT). We therefore evaluated the clinical efficacy of percutaneous transhepatic treatment for biliary leaks in adult‐to‐adult LDLT recipients. Twenty‐three LDLT recipients underwent percutaneous transhepatic treatment to manage bile leaks. The treatment included percutaneous transhepatic biliary drainage (PTBD) and drainage of perihepatic biloma.

C. Burcin Taner, Murat Dayangac, Baris Akin, Deniz Balci, Suleyman Uraz, Cihan Duran, Refik Killi, Omer Ayanoglu, Yildiray Yuzer, Yaman Tokat – 30 July 2008 – Living donor liver transplantation is now a common practice in countries in which the availability of cadaveric organs is limited. The preoperative preparation, intraoperative surgical technique, and postoperative care of donors and recipients have evolved in recent years.

Susumu Eguchi, Mitsuhisa Takatsuki, Masaaki Hidaka, Koji Hamasaki, Kensuke Miyazaki, Takamitsu Inokuma, Tetsuo Tomonaga, Yoshitsugu Tajima, Tatsuki Ichikawa, Takashi Kanematsu – 30 July 2008

Justin Sang Ko, Mi Sook Gwak, Soo Joo Choi, Gaab Soo Kim, Jie Ae Kim, Mikyung Yang, Sangmin Maria Lee, Hyun Sung Cho, In Sun Chung, Myung Hee Kim – 30 July 2008 – Various volatile anesthetics have been used in hepatectomy in living donors, and their effects on major organs have been extensively evaluated. However, the impact of total intravenous anesthesia (TIVA) on postoperative liver and renal functions after large liver resections has been less extensively investigated than that of volatile agents.