Use of splenic artery embolization to relieve tense ascites following liver transplantation in a patient with paroxysmal nocturnal hemoglobinuria

Charissa Y. Chang, Ashwani K. Singal, Sri V. Ganeshan, Thomas D. Schiano, Robert Lookstein, Sukru Emre – 29 October 2007 – Recurrent venous thrombosis following liver transplantation for Budd‐Chiari syndrome is common, particularly in the setting of an underlying myeloproliferative disorder. We describe a patient who developed refractory ascites due to portal vein thrombosis following liver transplantation for Budd‐Chiari syndrome in the setting of paroxysmal nocturnal hemoglobinuria.

Keratins let liver live: Mutations predispose to liver disease and crosslinking generates Mallory‐Denk bodies

Nam‐On Ku, Pavel Strnad, Bi‐Hui Zhong, Guo‐Zhong Tao, M. Bishr Omary – 29 October 2007 – Keratin polypeptides 8 and 18 (K8/K18) are the cytoskeletal intermediate filament proteins of hepatocytes while K8/K18/K19 are the keratins of hepatobiliary ductal cells. Hepatocyte K8/K18 are highly abundant and behave as stress proteins with injury‐inducible expression.

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