Molecular and clinical perspectives of polyomaviruses: Emerging evidence of importance in non‐kidney transplant populations

Regis A. Vilchez, Shimon Kusne – 26 September 2006 – JC virus (JCV), BK virus (BKV) and simian virus 40 (SV40) are deoxyribonucleic acid (DNA) viruses, members of the family Polyomaviridae. These viruses establish persistent infections, and reactivate from latency in their host under immunosuppression. During the last few years there has been recognition of the morbidity related to polyomaviruses, particularly BKV in kidney transplant recipients.

Early immunosuppression withdrawal after living donor liver transplantation and donor stem cell infusion

Vincent Donckier, Roberto Troisi, Alain Le Moine, Michel Toungouz, Salvatore Ricciardi, Isabelle Colle, Hans Van Vlierberghe, Ligia Craciun, Myriam Libin, Marleen Praet, Lucien Noens, Patrick Stordeur, Marc Andrien, Micheline Lambermont, Michel Gelin, Nadine Bourgeois, Michael Adler, Bernard de Hemptinne, Michel Goldman – 26 September 2006 – Long‐term results of organ transplantation are still limited by serious side effects of immunosuppressive drugs.

Single center experience of 39 patients with preoperative portal vein thrombosis among 404 adult living donor liver transplantations

Hiroto Egawa, Koichi Tanaka, Mureo Kasahara, Yasutsugu Takada, Fumitaka Oike, Kohei Ogawa, Seisuke Sakamoto, Koichi Kozaki, Kaoru Taira, Takashi Ito – 26 September 2006 – Living donor liver transplantation (LDLT) for patients with portal vein thrombosis (PVT) involves technical difficulty. The aim of this research was to analyze their preoperative diagnosis of PVT, operative procedures, and postoperative courses of patients with preoperative PVT.

The role of TIPS for portal vein patency in liver transplant patients with portal vein thrombosis

Jason Bauer, Stephen Johnson, Janette Durham, Michael Ludkowski, James Trotter, Thomas Bak, Michael Wachs – 26 September 2006 – The purpose of this research was to study the efficacy and outcomes of transjugular intrahepatic shunt (TIPS) in end‐stage liver disease (ESLD) patients with portal vein thrombosis (PVT) eligible for orthotopic liver transplant. Nine consecutive patients with PVT underwent TIPS as a nonemergent elective outpatient procedure. The primary indication for TIPS was to maintain portal vein patency for optimal surgical outcome.

An analysis of the UNOS liver transplant registry: High serum alpha‐fetoprotein does not justify an increase in MELD points for suspected hepatocellular carcinoma

Nyingi Kemmer, Guy Neff, Tiffany Kaiser, Victoria Zacharias, Mark Thomas, Amit Tevar, Supriya Satwah, Rakesh Shukla, Joseph Buell – 26 September 2006 – The current United Network for Organ Sharing (UNOS) criteria for liver transplantation gives priority to patients with elevated serum alpha‐fetoprotein (AFP; ≥ 500 ng/mL) in the absence of radiologic evidence of a hepatic mass. Reports have shown that an elevated serum AFP is a poor diagnostic indicator for hepatocellular carcinoma (HCC) in patients with cirrhosis.

Subscribe to