Geographic disparities in deceased donor liver transplantation within a single UNOS region

Neal R. Barshes, Natasha S. Becker, W. Kenneth Washburn, Glenn A. Halff, Thomas A. Aloia, John A. Goss – 24 April 2007 – Although the Model for End‐Stage Liver Disease (MELD) scoring system has improved the ability to measure medical urgency for transplantation, geographic disparities in the probability of being delisted as a result of complications of end‐stage liver disease or death and in the probability of orthotopic liver transplantation (OLT) remain.

Can antiplatelet prophylaxis reduce the incidence of hepatic artery thrombosis after liver transplantation?

Marco Vivarelli, Giuliano La Barba, Alessandro Cucchetti, Augusto Lauro, Massimo Del Gaudio, Matteo Ravaioli, Gian Luca Grazi, Antonio D. Pinna – 24 April 2007 – To ascertain whether postoperative antiplatelet therapy could reduce the incidence of hepatic artery thrombosis (HAT) after liver transplantation (LT), 838 consecutive adult whole‐graft LTs performed from April 1986 to August 2005 that survived beyond the first postoperative month were reviewed.

Trends in post–liver transplant survival in patients with hepatitis C between 1991 and 2001 in the united states

Paul J. Thuluvath, Karen L. Krok, Dorry L. Segev, Hwan Y. Yoo – 24 April 2007 – It has been suggested that the post–liver transplantation (LT) survival rate of patients with hepatitis C virus infection (HCV) has declined in recent years. To compare the outcome of LT in patients with HCV at various time intervals between 1991 and 2001, we used United Network for Organ Sharing data to compare the post‐LT survival of adult patients (age >18 years) with HCV with those without HCV.

Hepatitis C recurrence and fibrosis progression are not increased after living donor liver transplantation: A single‐center study of 289 patients

Maximilian Schmeding, Ulf Peter Neumann, Gero Puhl, Marcus Bahra, Ruth Neuhaus, Peter Neuhaus – 24 April 2007 – Today, hepatitis C virus (HCV) is the leading cause for liver transplantation (LT) and viral recurrence is almost universal. It has been suggested that viral replication within the transplanted tissue might be increased in organs of reduced size such as LD grafts. In the current literature the data is controversial, with many studies lacking routine liver biopsies.

Salvage living donor liver transplantation after prior liver resection for hepatocellular carcinoma

Shin Hwang, Sung‐Gyu Lee, Deok‐Bog Moon, Chul‐Soo Ahn, Ki‐Hun Kim, Young‐Joo Lee, Tae‐Yong Ha, Gi‐Won Song – 24 April 2007 – Salvage liver transplantation has been performed for recurrent hepatocellular carcinoma (HCC) or deterioration of liver function after primary liver resection. Because prior liver resection per se is an unfavorable condition for living donor liver transplantation (LDLT), we assessed the technical feasibility of LDLT after prior hepatectomy, and we compared the outcome of salvage LDLT with that of primary LDLT in HCC patients.

Early and late outcome of cardiac surgery in patients with liver cirrhosis

Farzan Filsoufi, Sacha P. Salzberg, Parwis B. Rahmanian, Thomas D. Schiano, Hussien Elsiesy, Anthony Squire, David H. Adams – 10 April 2007 – Liver cirrhosis is a major risk factor in general surgery. Few studies have reported on the outcome of cardiac surgery in these patients. Herein we report our recent experience in this high‐risk patient population according to the Child‐Turcotte‐Pugh classification and Model for End‐Stage Liver Disease (MELD) score.

Comparison of two techniques of transarterial chemoembolization before liver transplantation for hepatocellular carcinoma: A case‐control study

Sébastien Dharancy, Jeanne Boitard, Thomas Decaens, Géraldine Sergent, Emmanuel Boleslawski, Christophe Duvoux, Claire Vanlemmens, Carole Meyer, Jean Gugenheim, François Durand, Olivier Boillot, Nicole Declerck, Alexandre Louvet, Valérie Canva, Olivier Romano, Olivier Ernst, Philippe Mathurin, François René Pruvot – 10 April 2007 – Supraselective transarterial chemoembolization (STACE) more efficiently targets chemotherapy delivered via the feeding arterial branches of the tumor than does conventional transarterial chemoembolization (TACE).

Distinct effects of surgical denervation on hepatic perfusion, bowel ischemia, and oxidative stress in brain dead and living donor porcine models

Markus Golling, Cosima Jahnke, Hamidreza Fonouni, Rezvan Ahmadi, Renate Urbaschek, Raoul Breitkreutz, Peter Schemmer, Thomas W. Kraus, Martha M. Gebhard, Markus W. Büchler, Arianeb Mehrabi – 29 March 2007 – The liver function and perfusion following brain death is mainly influenced by the sympathetic nerves and hormones. We examined the specific influence of surgical liver denervation on systemic and hepatic perfusion parameters, bowel ischemia and oxidative stress in hemodynamically stable BD and control (living donor [LD]) pigs.

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