A functional polymorphism in the IL‐10 promoter influences the response after vaccination with HBsAg and hepatitis A

Thomas Höhler, Esther Reuss, Christine M. Freitag, Peter M. Schneider – 25 May 2005 – The immune response to hepatitis B surface antigen (HBsAg) is mostly genetically determined. Interleukin 10 (IL‐10) is a central immunoregulatory cytokine with important effects on B‐cells. We have studied the influence of IL‐10 promoter polymorphisms on the immune response to HBsAg and hepatitis A vaccination. We vaccinated 202 twin pairs in an open prospective study with a combined recombinant HBsAg/inactivated hepatitis A vaccine.

Hepatic targeting of transplanted liver sinusoidal endothelial cells in intact mice

Daniel Benten, Antonia Follenzi, Kuldeep K. Bhargava, Vinay Kumaran, Christopher J. Palestro, Sanjeev Gupta – 25 May 2005 – Targeting of cells to specific tissues is critical for cell therapy. To study endothelial cell targeting, we isolated mouse liver sinusoidal endothelial cells (LSEC) and examined cell biodistributions in animals.

Transmission of an undiagnosed sarcoma to recipients of kidney and liver grafts procured in a non‐heart beating donor

Olivier Detry, Arnaud De Roover, Laurence de Leval, Christian Herens, Jean Delwaide, Pierre Honoré, Michel Meurisse – 24 May 2005 – Transmission of an undiagnosed cancer with solid organ transplantation is a rare but dreadful event. In this paper the authors report the transmission of an undiagnosed sarcoma to recipients of kidney and liver grafts procured in a Maastricht category 3 non‐heart beating donor. To the authors' knowledge this case is the first report of such a transmission with a liver graft procured in a non‐heart beating donor.

Cryopreserved iliac artery is indispensable interposition graft material for middle hepatic vein reconstruction of right liver grafts

Shin Hwang, Sung‐Gyu Lee, Chul‐Soo Ahn, Kwang‐Min Park, Ki‐Hun Kim, Deok‐Bog Moon, Tae‐Yong Ha – 24 May 2005 – Cryopreserved iliac vein grafts (IVGs) have often been used for reconstruction of middle hepatic vein (MHV) branches in right liver grafts, but their storage pool has often been exhausted in our institution due to the low incidence of deceased donor organ procurement. To overcome this shortage of IVG, we started to use cryopreserved iliac artery graft (IAG).

Subscribe to