Philip Meuleman, Louis Libbrecht, Rita De Vos, Bernard de Hemptinne, Kris Gevaert, Joël Vandekerckhove, Tania Roskams, Geert Leroux‐Roels – 24 March 2005 – A small animal model harboring a functional human liver cell xenograft would be a useful tool to study human liver cell biology, drug metabolism, and infections with hepatotropic viruses. Here we describe the repopulation, organization, and function of human hepatocytes in a mouse recipient and the infections with hepatitis B virus (HBV) and hepatitis C virus (HCV) of the transplanted cells.

Vincent Di Martino, Pascal Lebray, Thierry Poynard – 24 March 2005

Margarita Sala, Josep M. Llovet, Jordi Bruix – 24 March 2005

Mical Campbell, Yu‐Xiao Yang, K. Rajender Reddy – 24 March 2005

Chun‐Yi Lu, Yen‐Hsuan Ni, Mei‐Hwei Chang, Chin‐Yun Lee, Li‐Min Huang – 24 March 2005

Hisamitsu Hayashi, Tappei Takada, Hiroshi Suzuki, Hidetaka Akita, Yuichi Sugiyama – 24 March 2005 – Progressive familial intrahepatic cholestasis type 2 (PFIC2) is caused by a mutation in the bile salt export pump (BSEP/ABCB11) gene. However, the mechanisms for the deficiency in the function of two mutations (E297G and D482G), which are frequently found in European patients, have not yet been identified. In the present study, we examined the transport activity and cellular localization of these two mutants in human embryonic kidney 293 and Madin‐Darby canine kidney II cells, respectively.

Benjamin L. Shneider, Piero Rinaldo, Sukru Emre, John Bucuvalas, Robert Squires, Michael Narkewicz, Gabriel Gondolesi, Margret Magid, Raffaella Morotti, Linda S. Hynan – 24 March 2005 – The etiology of acute liver failure in children is unknown in a large number of cases. Defects in fatty acid oxidation have been shown to lead to severe liver injury. This retrospective analysis examined the bile acylcarnitine profiles of 27 children with acute liver failure who underwent liver transplantation or died.

Estella M. Alonso – 23 March 2005

Naga Chalasani – 23 March 2005

Kyong‐Mi Chang – 23 March 2005