Herpes zoster infection after liver transplantation: A case‐control study

Josh Levitsky, Andre Kalil, Jane L. Meza, Glenn E. Hurst, Alison Freifeld – 17 February 2005 – Prior case series have suggested that herpes zoster (HZ) after orthotopic liver transplantation (OLT) may lead to serious complications due to visceral involvement. We sought to determine the incidence, risk factors, and long term outcomes of HZ after OLT. Clinical data from September 1993 to April 2004 were collected on all cases of HZ after OLT, and at the same post‐OLT time points in age, gender, and transplant‐year–matched HZ‐negative controls.

The development of food allergy after liver transplantation

Robert J. Boyle, Winita Hardikar, Mimi L.K. Tang – 17 February 2005 – The acquisition of new food allergy after orthotopic liver transplantation is now a well described phenomenon, mainly reported in children. The etiology of this phenomenon is at present unclear, but has been ascribed by some to tacrolimus treatment. Here we report a case of liver transplant acquired food allergy (LTAFA) in a child who received a split liver graft. The case is remarkable for the absence of new food allergy in the adult recipient of the same graft.

Cystatin C, an easy and reliable marker for assessment of renal dysfunction in children with liver disease and after liver transplantation

Marianne Samyn, Paul Cheeseman, Lynsey Bevis, Rachel Taylor, Beatrice Samaroo, Muriel Buxton‐Thomas, Nigel Heaton, Mohamed Rela, Giorgina Mieli‐Vergani, Anil Dhawan – 17 February 2005 – Renal dysfunction of variable severity is being increasingly recognized as a major complication of calcineurin inhibitors (CI), in some patients even necessitating renal transplantation. Close and effective monitoring of the renal function is indicated. Current methods for this monitoring are calculation of the glomerular filtration rate (GFR) based on creatinine or exogenous substances like 51Cr‐EDTA.

Reconstruction of the middle hepatic vein tributary in a right lateral sector graft

Takuya Hashimoto, Yasuhiko Sugawara, Yoji Kishi, Nobuhisa Akamatsu, Yuichi Matsui, Norihiro Kokudo, Masatoshi Makuuchi – 17 February 2005 – A right lateral sector graft (RLSG) was devised to overcome graft‐size disparity in living donor liver transplantation (LDLT). When the RLSG has a middle hepatic vein (MHV) tributary, which drains a significant part of segment VI, the MHV tributary (V6) should be reconstructed to avoid congestion of the RLSG.

Immunosuppression in liver transplantation: Beyond calcineurin inhibitors

John Fung, Dympna Kelly, Zakiyah Kadry, Kusum Patel‐Tom, Bijan Eghtesad – 17 February 2005 – Although calcineurin inhibitors (CNIs) remain the mainstay of immunosuppression in liver transplantation (LTX), their long‐term toxicity significantly contributes to morbidity and mortality. The elucidation of mechanisms of alloimmunity and leukocyte migration have provided novel targets for immunosuppression development. The toxicities of these agents differ from that of the CNI and act additively or synergistically.

Liver transplantation with simultaneous removal of an intracardiac transjugular intrahepatic portosystemic shunt and a vena cava filter without the utilization of cardiopulmonary bypass

Paolo R.O. Salvalaggio, Alan J. Koffron, Jonathan P. Fryer, Michael M. Abecassis – 21 January 2005 – Transjugular intrahepatic shunts (TIPSs) are widely used in the management of portal hypertension complications including variceal bleeding, refractory ascites, and hepatic hydrothorax. Vena cava filters (VCFs) are an important therapeutic modality in the prevention of pulmonary emboli in patients suffering deep venous thrombosis and clinical contraindications for anticoagulation. Stent and filter misplacement or migration may occur, complicating liver transplantation (LT) surgery.

Noninvasive ventilation for pediatric patients including those under 1‐year‐old undergoing liver transplantation

Kazuo Chin, Shinji Uemoto, Ken‐ichi Takahashi, Hiroto Egawa, Mureo Kasahara, Yasuhiro Fujimoto, Kensuke Sumi, Michiaki Mishima, Colin E. Sullivan, Kouichi Tanaka – 21 January 2005 – Pulmonary complications are an important cause of the mortality associated with liver transplantation. The efficacy of noninvasive ventilation (NIV) in pediatric patients following transplantation is unknown. The purpose of this retrospective study is to investigate the effects of NIV for pediatric patients undergoing liver transplantation.

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