C/EBP β isoforms LIP and LAP modulate progression of the cell cycle in the regenerating mouse liver
Tom Luedde, Moritz Duderstadt, Konrad L. Streetz, Frank Tacke, Stefan Kubicka, Michael P. Manns, Christian Trautwein – 13 August 2004 – The CCAAT enhancer‐binding protein (C/EBP) β gene can produce several N‐terminally truncated isoforms. Liver‐enriched activator protein (LAP) is a transcriptional activator in many systems, whereas liver‐enriched inhibitory protein (LIP) is regarded as a functional LAP antagonist. In this study, we examined the impact of these two proteins on cell cycle progression in the regenerating liver.