Immunoglobulin‐G subclass antidonor reactivity in transplant recipients
Zu‐hua Gao, Vivian C. McAlister, James R. Wright, Chloe C. McAlister, Kevork Peltekian, Allan S. MacDonald – 23 July 2004 – Outcomes may differ after kidney transplantation compared to combined liver‐kidney transplantation. In animal models, distinct patterns of antidonor immunoglobulin (Ig) G subclasses are associated with either rejection or transplant tolerance. Flow cytometry has increased the sensitivity of antidonor immunoglobulin detection. We compared antidonor IgG subclass responses in kidney transplant recipients to those in recipients of liver or multiorgan grafts.