Michael J. Guirl, Jeffrey S. Weinstein, Robert M. Goldstein, Marlon F. Levy, Goran B. Klintmalm – 22 March 2004 – Two‐stage total hepatectomy and liver transplantation has been reported for acute liver disease such as fulminant hepatic failure, primary graft failure, severe hepatic trauma, and spontaneous hepatic rupture secondary to hemolysis, elevated liver function tests, low platelets syndrome, and preeclampsia. This is the first report of patients with cirrhosis to undergo a 2‐stage total hepatectomy and liver transplantation.

Chi‐Leung Liu, See‐Ching Chan, Chung‐Mau Lo, Wai‐Kuen Tso, Sheung‐Tat Fan – 22 March 2004

James Neuberger, Bridget Gunson, Stefan Hubscher, Peter Nightingale – 22 March 2004 – Identifying the risk factors associated with recurrence of primary biliary cirrhosis after liver transplantation may affect immunosuppression and increase understanding of the pathogenesis. Four hundred eighty‐five patients with PBC were followed for a median of 79 months after transplantation; histological evidence of recurrence was found in 23%. On multivariate analysis, the only risk factor identified with recurrence was the type of calcineurin inhibitor used.

Mark D. Stegall, Jeffrey L. Platt – 22 March 2004

Juan Córdoba, Roy Lucke – 27 February 2004

Alexander Monto, Keyur Patel, Alan Bostrom, Stephen Pianko, Paul Pockros, John G. McHutchison, Teresa L. Wright – 27 February 2004 – Heavy alcohol use contributes to liver disease in the setting of chronic hepatitis C virus (HCV) infection. Whether this is true for light or moderate alcohol use has not been demonstrated. Light alcohol use has survival benefits at a population level and is practiced by most patients with chronic HCV infection.

Henning Schulze‐Bergkamen, Dirk Brenner, Andreas Krueger, Dorothee Suess, Stefanie C. Fas, Christian R. Frey, Andreas Dax, Dorothea Zink, Peter Büchler, Martina Müller, Peter H. Krammer – 27 February 2004 – CD95 (APO‐1/Fas)‐mediated apoptosis of hepatocytes plays a central role in the pathophysiology of various human liver diseases. Hepatocyte growth factor (HGF) was shown to exert antiapoptotic functions in rodent hepatocytes. We previously showed that primary human hepatocytes (PHH) are a valuable tool for the investigation of apoptotic processes in liver cells.

Michael Kann – 27 February 2004

M. Deschênes, Pierre Laneuville – 27 February 2004

Giovanna Vona, Laurence Estepa, Christophe Béroud, Diane Damotte, Frédérique Capron, Bertrand Nalpas, Alexandra Mineur, Dominique Franco, Bernard Lacour, Stanislas Pol, Christian Bréchot, Patrizia Paterlini‐Bréchot – 27 February 2004 – The clinical impact of circulating tumor cell (CTC) detection is controversial, mainly due to drawbacks of molecular approaches applied to this field. We sought to determine if the specific identification and counting of circulating tumor cells by cytomorphologic analysis has clinical usefulness.