Rhesus rotavirus receptor‐binding site affects high mobility group box 1 release, altering the pathogenesis of experimental biliary atresia

Sujit K. Mohanty, Bryan Donnelly, Haley Temple, Sarah Mowery, Holly M. Poling, Jaroslaw Meller, Astha Malik, Monica McNeal, Greg Tiao – 21 July 2022 – Biliary atresia (BA) is a neonatal inflammatory cholangiopathy that requires surgical intervention by Kasai portoenterostomy to restore biliary drainage. Even with successful portoenterostomy, most patients diagnosed with BA progress to end‐stage liver disease, necessitating a liver transplantation for survival.

Acute hepatitis of unknown origin in children: Behind the statistics

Randa Elsheikh, Hoang Thuy Tien, Abdelrahman M. Makram, Nguyen Thanh Van, Trang Thi Bich Le, Tamilarasy Vasanthakumaran, Nguyen Tien Huy – 20 July 2022 – Since April 2022, the world has been witnessing a rapidly spreading outbreak of acute hepatitis of unknown origin in children < 16 years old that has affected several countries around the world. Most of the cases have presented with the clinical picture of severe hepatitis that has led to resorting to liver transplantation in several cases.

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