Coagulation techniques are not important in directing blood product transfusion during liver transplantation

M Reyle‐Hahn, R Rossaint – 30 December 2003 – Preoperative acquired clotting parameters such as prothrombin time, activated partial thromboplastin time, antithrombin III, platelet concentration, and fibrinogen show coagulopathy caused by insufficiency of the diseased liver.

Hepatic artery resistance index can predict early death in children with biliary atresia

E Broide, P Farrant, F Reid, A Baker, H Meire, M Rela, M Davenport, N Heaton, G Mieli‐Vergani – 30 December 2003 – Hepatic artery resistance index has been measured by ultrasonography Doppler and has been found to predict rapid deterioration and death in children with biliary atresia. Clinical, biochemical, ultrasonographic, and outcome data were collected prospectively and retrieved on 32 patients with resistance index of > or = 1.0 (group A). These were compared with the same data for 32 age‐ and sex‐matched patients with biliary atresia and a resistance index of ≤ 1.0 (group B).

Comparison of histopathology in acute allograft rejection and recurrent hepatitis C infection after liver transplantation

L M Petrovic, F G Villamil, J M Vierling, L Makowka, S A Geller – 30 December 2003 – Recurrent hepatitis C infection after orthotopic liver transplantation (OLT) is frequent and may occur as early as a few weeks postoperatively. Early histopathological features of recurrent hepatitis C virus (HCV) infection may be modified by immunosuppressive therapy and can be difficult to differentiate from acute allograft rejection (AAR).

Portal vein complications after liver transplantation for biliary atresia

C Chardot, J M Herrera, D Debray, S Branchereau, O De Dreuzy, D Devictor, B Dartayet, P Norwood, T Lambert, D Pariente, F Gauthier, J Valayer – 30 December 2003 – The objective of this report is to review portal complications (PC) after pediatric liver transplantation (LT) for biliary atresia (BA) in the Bicetre surgical series. From January 1, 1988, to February 28, 1995, 96 children with BA underwent 115 LTs Portal anastomosis was done on either the recipient portal vein (n = 85) or superior mesenteric vein (n = 11). No antiaggregative agents were administered postoperatively.

Immunonephelometric quantification of group‐specific component protein in patients with acute liver failure

F H Wians, W Lin, L P Brown, F V Schiodt, W M Lee – 30 December 2003 – Serum levels of group‐specific component (Gc) protein are useful in evaluating the likelihood of survival in patients with acute liver failure (ALF) who may be candidates for liver transplant surgery. Most methods for quantifying Gc protein concentration are either isotopic, manual, technically demanding, and/or time consuming to perform, and thus are not well suited for routine clinical use in a hospital setting.

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