General considerations in the management of patients with depressed consciousness and chronic hepatic insufficiency
Jeffrey I. Frank – 1 September 1995
Issues in xenotransplantation absence of hyperacute rejection in newborn pig‐to‐baboon cardiac xenografts
Nancy L. Ascher – 1 September 1995 – The shortage of organs for transplantation is especially severe for the critically ill newborn infant, for whom donors of the appropriate size are particularly scarce. One way to overcome this problem is to use animals in lieu of human as organ donors. The major limitation to using animals for this purpose is the susceptibility of animal organs to hyperacute rejection, a violent rejection reaction thought to be mediated by antidonor antibody and complement.
Alveolar echinococcosis
François Mosimann, Solange Bresson‐Hadni, Georges Mantion, Michel Gillet, Rudolf W. Ammann – 1 September 1995
Ursodeoxycholic acid for chronic hepatitis C patients
Claudio Puoti, Andrea Magrini, Gloria Annovazzi, Alfonsa Pannullo, Teresa Filippi – 1 September 1995
How to tell the truth and avoid the urge to lie: Planning a career in medical research
Amnon Sonnenberg – 1 September 1995
Downregulation of phorbol 12‐myristate 13‐acetate–induced tumor necrosis factor–alpha and interleukin‐1β production and gene expression in human monocytic cells by human alpha‐fetoprotein
Wei Wang, Elliot Alpert – 1 September 1995 – We previously identified a specific receptor for alpha‐fetoprotein (AFP) on human monocytes. Although AFP alters many immune cell functions, the effect of AFP on monocyte cytokine production is unknown. Because tumor necrosis factor–alpha (TNF‐α) and interleukin‐1β (IL‐1β) are important cytokines in immunoregulation, we investigated whether AFP could modulate TNF‐α and IL‐1β production in U937, a human monocytic cell line.
Diclofenac‐associated hepatotoxicity: Analysis of 180 cases reported to the food and drug administration as adverse reactions
Alpha T. Banks, Hyman J. Zimmerman, Kamal G. Ishak, John G. Harter – 1 September 1995 – Diclofenac is a nonsteroidal anti–inflammatory drug approved in the United States in 1988 for the treatment of patients with osteoarthritis, rheumatoid arthritis, or ankylosing spondylitis.
Differential expression and release of CD54 induced by cytokines
Judith K. Mickelson, Gilbert Kukielka, J. Stanley Bravenec, Elizabeth Mainolfi, Robert Rothlein, Hal K. Hawkins, James H. Kelly, C. Wayne Smith – 1 September 1995 – Intercellular adhesion molecule‐1 (ICAM‐1, CD54) is upregulated in many cell types stimulated by cytokines.
Mucin‐vesicle interactions in model bile: Evidence for vesicle aggregation and fusion before cholesterol crystal formation
Nezam H. Afdhal, Niu Niu, David P. Nunes, Rama Bansil, Xing Xiang Cao, Donald Gantz, Donald M. Small, Gwynneth D. Offner – 1 September 1995 – Nucleation of cholesterol monohydrate crystals from bile is a critical step in the formation of cholesterol gallstones. Measurement of nucleation in model bile systems and the characteristics of the initial nucleus have proven elusive.