Shuichi Hanada, Takaji Wakita, Hiroshi Takahashi – 1 November 1994 – Fusion of BERH‐2 rat hepatocellular carcinoma cells with activated B cells produced hybrid cells that lost their tumorigenicity and became immunogenic. Syngeneic rats injected with BERH‐2‐B hybrid cells became resistant to challenge with parental BERH‐2 cells, and rats with established BERH‐2 hepatomas were cured by subsequent injection of BERH‐2‐B cells. Both CD4 and CD8+ cells were essential for the induction of protective immunity; however, only CD8+ cells were required for the eradication of BERH‐2 tumors.

William J. Parks – 1 November 1994

Jurgen Ludwig, Charles B. Rosen, Keith D. Lindor, John H. Helzberg, Kenneth R. Watson – 1 November 1994

Satoshi Ishiguro, Shigeki Arii, Kazunobu Monden, Yukito Adachi, Naomi Funaki, Hiroaki Higashitsuji, Shin‐Ichi Fujita, Masaharu Furutani, Masahiro Mise, Tadahiro Kitao, Toshio Nakamura, Fumitaka Ushikubi, Ken‐Ichi Nakamura, Shuh Narumiya, Katsuhiko Enomoto, Tousei Ohmura, Michio Mori, Masayuki Imamura – 1 November 1994 – The presence of the thromboxane A2 receptor in sinusoidal endothelial cells was investigated and its pathogenic role in endotoxin‐induced liver injury examined. The receptor was measured with a binding assay using a specific thromboxane A2 receptor antagonist, [3H]S‐145.

Teresa L. Wright, Harry Hollander, Xiang Pu, Michael J. Held, Peter Lipson, Stella Quan, Alan Polito, M. Michael Thaler, Peter Bacchetti, Bruce F. Scharschmidt – 1 November 1994 – Background: Limited information is available about the prevalence of hepatitis C virus in patients with human immunodeficiency virus in relation to specific risk factors or about the influence of hepatitis C virus coinfection on survival. This retrospective study addressed these questions.

Gianfranco Tappero, Gioacchino Natoli, Giovanni Anfossi, Floriano Rosina, Francesco Negro, Antonina Smedile, Ferruccio Bonino, Alberto Angeli, Robert H. Purcell, Professor Mario Rizzetto, Massimo Levrero – 1 November 1994 – The intrahepatic accumulation of the c‐myc protooncogene product was observed on immunoflourescence in each of six patients with chronic hepatitis delta virus infection who exhibited the hepatitis D antigen in their livers. The c‐myc product was stained in the same nuclei that contained the hepatitis D antigen.

Kirk Sperber – 1 November 1994

Alan F. Hofmann, James M. Crawford – 1 November 1994

Kenneth Jensen, Christian Gluud – 1 November 1994 – Drawing on data from a previously published literature survey on the clinical and experimental epidemiology of the Mallory body, we discuss current theories on its development in a pro et contra manner. Conclusions have been largely left open to the interpretations of the reader because many are still speculative. The main results of this study characterize Mallory bodies as stereotypical histological byproducts to diverse hepatic injuries (mostly alcohol associated) of questionable pathogenic importance.

Hiroaki Shimizu, Wei He, Ping Guo, Irena Dziadkoviec, Masaru Miyazaki, Rudolf E. Falk – 1 November 1994 – This study was designed to evaluate the use of serum hyaluronate as a marker of liver endothelial cell function after liver transplantation. We performed orthotopic liver transplantation in both isogeneic and allogeneic rejector models. After transplantation, hepatocyte function was assessed on the basis of serum ALT and total bilirubin levels, and liver endothelial cell function was judged on the basis of serum hyaluronate levels.