Ramón Vilana, Jordi Bruix, Concepció Bru, Carmen Ayuso, Manel Solé, Joan Rodés – 1 August 1992 – This study was aimed at defining the therapeutic value of percutaneous ethanol injection in patients with solitary hepatocellular carcinoma less than 4 cm. Ultrasound‐guided ethanol injection was performed in 24 cirrhotic patients (9 Child A, 10 Child B and 5 Child C), with hepatocellular carcinoma not suitable for surgical treatment. Its efficacy was assessed by repeated ultrasound, computed tomography and tumor biopsy during a follow‐up ranging between 4 and 41 mo.

Naoki Hiramatsu, Norio Hayashi, Yoshimichi Haruna, Akinori Kasahara, Hideyuki Fusamoto, Chisato Mori, Isao Fuke, Hiroto Okayama, Takenobu Kamada – 1 August 1992 – The localization of hepatitis C virus–infected hepatocytes in the human liver remains unclear despite the development of a serological assay for the antibody to hepatitis C virus. We studied their localization immunohistochemically with monoclonal antibodies to core, envelope and NS3 antigens of hepatitis C virus.

James P. McManus – 1 August 1992

Teresa L. Wright – 1 August 1992

C. Minke Bakker, Herold J. Metselaar, Theo N. Groenland, Maria J. Gomes, Eduard A. R. Knot, Eric J. Hesselink, Solco W. Schalm, Jeanne Stibbe, Onno T. Terpstra – 1 August 1992 – The major cause of the increased tissue‐type plasminogen activator activity during orthotopic liver transplantation is still unclear. Both the lack of hepatic clearance of tissue‐type plasminogen activator in the anhepatic period and increased endothelial release from the graft on reperfusion have been proposed as the major causes.

1 August 1992

Paulette Bioulac‐Sage, Liliane Dubuisson, Christiane Bedin, Pierre Gonzalez, Eliane de Tinguy‐Moreaud, Henri Garcin, Charles Balabaud – 1 August 1992 – Weaned male rats were fed a 4 ppm selenium diet. Compared after 2 mo with a control group fed a 0.4 ppm diet, the rats' body weights had not significantly decreased and liver function was normal, but portal pressure was 1.8 times higher (p < 0.05). Liver weight was slightly increased (10.3%; p < 0.05). All livers had an abnormal appearance.

Anders Lindblad, Rolf Hultcrantz, Birgitta Strandvik – 1 August 1992 – To study the liver disease of patients with cystic fibrosis, percutaneous liver biopsies were performed in 10 patients with cystic fibrosis aged 6 to 22 yr.

Tetsuji Kida, Yasuni Nakanuma, Tadashi Terada – 1 August 1992 – Cystic dilatation of peribiliary glands of intrahepatic and extrahepatic bile ducts was investigated in autopsied livers with adult polycystic disease (n = 8), in autopsied livers with solitary nonparasitic cysts (n = 18) and in normal autopsied livers (n = 23). In normal livers, cystic dilatation of intrahepatic peribiliary glands was absent or slight, when present. In livers with solitary nonparasitic cysts, cystic dilatation of intrahepatic peribiliary glands was present in varying degrees.

Judith S. Gavaler, David H. van Thiel – 1 August 1992 – The derangements of levels of sex hormones and gonadotropins in alcoholic cirrhotic men are well delineated. The countersituation in alcoholic cirrhotic women has not yet been fully described. This study was performed in postmenopausal women among whom menstrual cycle variations in hormones no longer occur; with such a study population, it is possible to control for confounding factors and thus optimize detection of differences in levels of hormones and hormone interrelationships.