Inborn errors of metabolism. Edited by J. Schaub, F. Van Hoof and H.L. Vis, 298 pp. New York: Raven Press, 1991. $62
Raymond S. Koff – 1 October 1991
Current concepts in cell‐mediated hepatic allograft rejection leading to ductopenia and liver failure
Russell H. Wiesner, Jurgen Ludwig, Bart van Hoek, Ruud A. F. Krom – 1 October 1991
Superoxide is involved in the pathogenesis of paraquat‐induced injury in cultured rat liver slices
Hitoshi Togashi, Haruhide Shinzawa, Hiroto Wakabayashi, Toichiro Nakamura, Huang Yong, Nobuo Yamada, Katsuaki Ukai, Yoshimi Okuyama, Tsuneo Takahashi, Makoto Ishikawa – 1 October 1991 – We examined whether superoxide is a factor responsible for paraquat‐induced liver injury in terms of superoxide dismutase using cultured rat liver slices exposed to various concentrations of paraquat. The degree of liver injury was assessed by measurement of percentage of lactate dehydrogenase leakage into the medium and lipid hydroperoxides in the liver slices and by direct histopathological observation.
Urinary excretion of lithocholic acid and its conjugates by the bile duct–ligated rat
Joanna M. Little, Piotr Zimniak, Anna Radominska, Roger Lester, Paul Lehman – 1 October 1991 – The 3‐O‐glucuronide of lithocholic acid has been shown to be a potent cholestatic agent in rats. However, even after the onset of lithocholic acid glucuronide–induced cholestasis, little of the administered material was recovered in urine.
Dietary fish oil effects on biliary lipid secretion and cholesterol gallstone formation in the African green monkey
Martin W. Scobey, Fred L. Johnson, John S. Parks, Lawrence L. Rudel – 1 October 1991 – We studied two groups of adult male African green monkeys to assess the effects of dietary fish oil on biliary lipid secretion and cholesterol gallstone formation. One group was fed 0.8 mg cholesterol/kcal and 42% of calories as fat with half of the fat calories derived from lard; the other group was fed a similar diet except for the isocaloric substitution of menhaden oil for lard. After 21/2 to 3 yr, necropsies were performed and the presence of gallstones was determined.
Estrogen and progesterone receptors in the gallbladders from patients with gallstones
Franco O. Ranelletti, Mauro Piantelli, Everardo Zanella, Arnaldo Capelli, Attilio M. Farinon – 1 October 1991 – Cytosolic receptors for estrogen and progesterone were assayed in 50 gallbladders from 29 women and 21 men who had cholecystectomies because of choleithiasis. High‐affinity (equilibrium dissociation constant, KD = 0.46 ± 0.23 nmol/L of 24 cases) estrogen receptors were detected in 20 of 29 gallbladders from women (range = 1.6 to 32 fmol/mg protein; mean ± S.D. = 10.9 ± 8.1), whereas in men only 4 of 21 specimens contained detectable estrogen receptors.