Seroepidemiology of hepatitis C virus infection in Taiwan
Shou‐Dong Lee, Cho‐Yu Chan, Yan‐Jenn Wang, Jaw‐Ching Wu, Kwok‐Hung Lai, Yang‐Te Tsai, Kwang‐Juei Lo – 1 May 1991 – The prevalence of antibody to hepatitis C virus among Chinese subjects in Taiwan was evaluated using a commercially available enzyme immunoassay. The overall prevalence of antibody to hepatitis C virus was 0.28% among 1,419 healthy subjects, 0.8% among 500 unselected paid blood donors and 0.4% among 793 pregnant women.
Memory T cells represent the predominant lymphocyte subset in acute and chronic liver inflammation
Riccardo Volpes, Joost J. van den Oord, Valeer J. Desmet – 1 May 1991 – T cells can be divided into two main phenotypic subpopulations–i.e., the CD45RA‐positive (2H4‐positive) “naive” subset and the CD45RO‐positive (UCHL1‐positive) “memory” subset.
Sex hormones in postmenopausal women with primary biliary cirrhosis
Ulrik Becker, Thomas Almdal, Erik Christensen, Christian Gluud, Stense Farholt, Paul Bennett, Birgit Svenstrup, Finn Hardt – 1 May 1991 – To evaluate serum sex hormone profiles in nonalcoholic postmenopausal women with liver disease, 25 women with primary biliary cirrhosis (11 in cirrhotic stage) and 46 healthy controls were studied.
Morbidity and mortality from chronic hepatitis B virus infection in family members of patients with malignant and nonmalignant hepatitis B virus–related chronic liver diseases
Anna S. F. Lok, Ching‐Lung Lai, Hau‐Tim Chung, Johnson Y. N. Lau, Elsie K. Y. Leung, Loretta S. K. Wong – 1 May 1991 – Three‐hundred forty‐one HBsAg‐positive family members of 152 patients with chronic hepatitis B virus infection (47 asymptomatic carriers, 59 with chronic hepatitis, 17 with cirrhosis and 29 with hepatocellular carcinoma) were prospectively studied to determine the morbidity and mortality from chronic hepatitis B virus infection in the family members of patients with malignant and nonmalignant hepatitis B virus–related chronic liver diseases.
Spironolactone and canrenoate: Different antialdosteronic diuretic agents
Jorge J. Gumucio, Paolo Gentilini – 1 May 1991 – Plasma levels of canrenone and androgen receptoractive materials (ARM) were determined during long‐term oral K‐canrenoate or spironolactone therapy in cirrhotics with chronic recurrent ascites. Mean plasma canrenone level was approximately 3 times higher under K‐canrenoate than under spironolactone treatment; moreover, the levels were not dose related. Either type of treatment did not affect plasma aldosterone and testosterone concentrations.
Double‐blind investigation of the effects of propranolol and placebo on the pressure of esophageal varices in patients with portal hypertension
Faust Feu, Josep M. Bordas, Joan C. Garcia‐Pagán, Jaime Bosch, Joan Rodés – 1 May 1991 – This study was aimed at investigating the effects of propranolol on esophageal variceal pressure in patients with portal hypertension.
Independent risk factors for hepatocellular carcinoma in french drinkers
Thierry Poynard, Alain Aubert, Yasmina Lazizi, Pierre Bedossa, Bernard Hamelin, Benoit Terris, Sylvie Naveau, Pascal Dubreuil, Jacques Pillot, Jean‐Claude Chaput – 1 May 1991 – The aim of this study was to assess whether markers of hepatitis B virus or hepatitis C virus infection are independent risk factors for hepatocellular carcinoma in drinkers after adjustment for three known risk factors: cirrhosis, age and male sex. Among 2,015 consecutive drinkers admitted, hepatitis C virus antibodies were found by sensitive radioimmunoassay in 1,259.
Bioelectric impedance analysis: Experience with male patients with cirrhosis
Francesco William Guglielmi, Francesco Contento, Lucia Laddaga, Carmine Panella, Antonio Francavilla – 1 May 1991 – Bioelectric impedance analysis is a new, convenient and portable method used to estimate total body water and to assess body composition in healthy people. We used the tetrapolar bioelectrical impedance analysis method in 58 cirrhotic patients to assess its clinical applicability. Whole‐body resistance, reactance and impedance were measured and compared with those of 30 healthy volunteers matched for age and sex.