Excision of multiple metastases: Better designed studies are needed

Martin Adson – 1 March 1990 – Metastatic carcinoma to the liver is generally considered to be associated with a poor prognosis, with five year survival of only 20% to 30% after resection of solitary lesions. Ninety‐eight consecutive patients underwent the surgical removal of one to 13 metastatic lesions from the liver. A rising carcinoembryonic antigen level was considered an indication for reexploration. All gross tumor was removed in every patient; 66 had more than one metastasis.

Plasma des‐γ‐carboxyprothrombin in the early stage of hepatocellular carcinoma

Sun‐Lung Tsai, Guan‐Tarn Huang, Pei‐Ming Yang, Jin‐Chuan Sheu, Juei‐Low Sung, Ding‐Shinn Chen – 1 March 1990 – To evaluate the role of plasma des‐γ‐carboxyprothrombin in the early diagnosis of hepatocellular carcinoma, we simultaneously studied both des‐γ‐carboxyprothrombin activities by staphylocoagulase method and des‐γ‐carboxyprothrombin antigen levels by enzyme immunoassay in 39 patients with early stage hepatocellular carcinoma (tumor size <3 cm in 21 patients, 3 to 5 cm in 18 patients); 68 patients had large hepatocellular carcinoma and 54 patients had chronic hepatitis or cirrhosi

Spontaneous bacterial empyema in cirrhotic patients: Analysis of eleven cases

Xavier Xiol, Jose Castellote, Carme Baliellas, Javier Ariza, Ana Gimenez Roca, Jordi Guardiola, Luis Casais – 1 March 1990 – Eleven episodes of spontaneous bacterial empyema were identified in eight cirrhotic patients with ascites. Criteria for spontaneous bacterial empyema included positive pleural fluid culture or polymorphonuclear cell concentration >500 cells/mm3, evidence of pleural effusion before an infectious episode and transudate characteristics during infection.

Recurrence factors studied by percutaneous transpepatic portography before and after endoscopic sclerotherapy for esophageal varies

Yasuhiro Takase, Susumu Shibuya, Fumio Chikamori, Kazuo Orii, Yoji Iwasaki – 1 March 1990 – High recurrence and rebleding rates have been reported when endocopic sclerotherapy has been performed on patients with esophageal varices. We studied the relationship between embolization range and recurrence rate in 26 patients in whom percutaneous transhepatic portography was carried out before and after sclerotherapy. Patients were divided into complete and incomplete embolization groups. The complete and incomplete embolization groups.

Antibodies against the hepatic asialoglycoprotein receptor perfused In Situ preferentially attach to periportal liver cells in the rat

Barbara M. McFarlane, Jozsef Sipos, Christopher D. Gove, Ian G. McFarlane, Roger Williams – 1 March 1990 – Autoantibodies reacting with the galactose‐specific hepatic asialoglycoprotein receptor—a liver‐specific component expressed on the surfaces of hepatocytes—are often found in patients with chronic active hepatitis of presumed autoimmune origin.

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