Masthead
1 January 1986
Periductal fibrosis and lipocytes (fat‐storing cells or ito cells) during biliary atresia in the lamprey
Kazuhide Yamamoto, Patricia A. Sargent, Murray M. Fisher, John H. Youson – 1 January 1986 – Transmission and scanning electron microscopy were utilized to follow the degeneration of bile ducts of lampreys (Petromyzon marinus L.) during metamorphosis. The convoluted bile ducts of larval lampreys are surrounded by rich sinusoids, but this intimate biliovascular relationship is lost during metamorphosis because the bile duct degeneration is accompanied by the development of thick periductal fibrosis.
Terlipressin in bleeding esophageal varices: A placebo‐controlled, double‐blind study
Siegfried Walker M.D., Adolf Stiehl, Richard Raedsch, Burkhard Kommerell – 1 January 1986 – The effect of terlipressin (N‐α‐triglycyl‐8‐lysinevasopressin) in bleeding esophageal varices was evaluated in a prospective placebo‐controlled study. Fifty bleeding episodes from esophagealvarices in 34 patients were randomized. Standard therapy with transfusions, fluid and electrolyte correction, and lactulose was performed in both groups. Balloon tamponade was used in 20 bleeding episodes in the terlipressin group and in 19 bleeding episodes in the control group.
Hepatic hemodynamics and oxygen consumption in alcoholic fatty liver assessed by organ‐reflectance spectrophotometry and the hydrogen clearance method
Akinori Kasahara, Norio Hayashi, Kazuhei Kurosawa, Yutaka Sasaki, Nobuhiro Sato, Takenobu Kamada – 1 January 1986 – Hepatic blood flow and estimated hepatic oxygen consumption were studied in rats treated chronically with ethanol by organ‐reflectance spectrophotometry and the hydrogen clearance method.
Hemochromatosis: How much iron is too much?
Anthony S. Tavill, Bruce R. Bacon – 1 January 1986
Portal venous‐esophageal luminal pressure gradient in cirrhosis
Pierre Reding, Daniel Urbain, André Grivegnee, Daniel Frere – 1 January 1986 – The portal venous‐esophageal luminal pressure gradient may be more important than the absolute portal venous pressure in explaining hemorrhages caused by esophageal varices. A continuous recording of portal venous pressure and the esophageal luminal pressure enabled the authors to study the gradient between these pressures in 12 cirrhotic patients with varices of different size and under different circumstances, in particular inspiration, expiration, coughing and a Valsalva maneuver.
Effects of ethanol on experimental hepatocarcinogenesis
Akira Takada, Jinichi Nei, Shujiro Takase, Yoshiro Matsuda – 1 January 1986 – Although primary hepatoma is not very frequent in alcoholics, the incidence of hepatoma in cases of hepatitis B infection combined with heavy alcohol drinking is high. In the present study, the effects of chronic alcohol administration onthe development of chemicalinduced hepatic cancer in rats were analyzed. In 70% hepatectomized Wistar strain male rats, asingle dose (1 mg per 100 gm body weight) of diethylnitrosamine was injected intraperitoneally.
Hemagglutination and immunofluorescence studies on polymerized human serum albumin binding activity in chronic hepatitis B virus infection
Ignacio Mora, Juan Carlos Porres, Carlos Hernández Guio, Julia Gutiez, Vicente Carreño – 1 January 1986 – The binding activity of polymerized human serum albumin was determined in 202 HBsAg carriers. The presence of polymerized human serum albumin receptor sites was tested by hemagglutination and differentiated from antihuman albumin antibodies by immunofluorescence, isolation of IgG and IgM fractions and testing of HBsAg anti‐HBs immune complexes. A granular pattern with anti‐HBs was specific for polymerized human serum albumin receptor sites as demonstrated with purified HBsAg.