The relationship between glucagon and prostaglandin f in stimulating canine hepatic bile flow
D. L. Kaminski, Y. G. Deshpande – 1 March 1986 – Both glucagon and prostaglandin F2α have been shown to stimulate a chloride‐rich choleresis in dogs. This study was performed to ascertain the interrelationship between glucagon and prostaglandin F2α in stimulating bile flow. The experiments were performed using dogs with chronic biliary and gastric fistulas. Initially, the effects of prostaglandin F2α on serum glucagon levels were evaluated. Glucagon administration increased bile volume andchloride secretion as did prostaglandin F2α.