Acute Graft‐Versus‐Host Disease After Orthotopic Liver Transplantation: Predicting This Rare Complication Using Machine Learning

Jason P. Cooper, James D. Perkins, Paul R. Warner, Alexandra Shingina, Scott W. Biggins, Janis L. Abkowitz, Jorge D. Reyes – 28 September 2021 – Acute graft‐versus‐host disease (GVHD) is a rare complication after orthotopic liver transplantation (OLT) that carries high mortality. We hypothesized that machine‐learning algorithms to predict rare events would identify patients at high risk for developing GVHD.

The zinc finger and BTB domain containing protein ZBTB20 regulates plasma triglyceride metabolism by repressing lipoprotein lipase gene transcription in hepatocytes

Hao Li, Gan Liu, Xiaoqing Wan, Luting Zhou, Zhen‐Bang Qin, Xian‐Hua Ma, Kai Su, Ya‐Jin Liu, Jinghao Yuan, Chun‐Chun Wei, An‐Jing Ren, Yu‐Xia Chen, Stephen G. Young, Hai Zhang, Zhifang Xie, Weiping J. Zhang – 27 September 2021

Activation of p53 After Irradiation Impairs the Regenerative Capacity of the Mouse Liver

Makiko Urabe, Hayato Hikita, Yoshinobu Saito, Shinnosuke Kudo, Kenji Fukumoto, Naoki Mizutani, Yuta Myojin, Akira Doi, Katsuhiko Sato, Sadatsugu Sakane, Yuki Makino, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara – 27 September 2021 – Radiation therapy is one of the treatment methods for hepatocellular carcinoma. However, radiation tolerance of the liver is low, and the detailed effect of radiation on liver regeneration has not been clarified.

Low Serum Cholinesterase Identifies Patients With Worse Outcome and Increased Mortality After TIPS

Lena Stockhoff, Theresa Muellner‐Bucsics, Antoaneta A. Markova, Marie Schultalbers, Simone A. Keimburg, Tammo L. Tergast, Jan B. Hinrichs, Nicolas Simon, Svetlana Gerbel, Michael P. Manns, Mattias Mandorfer, Markus Cornberg, Bernhard C. Meyer, Heiner Wedemeyer, Thomas Reiberger, Benjamin Maasoumy – 27 September 2021 – Transjugular intrahepatic portosystemic shunt (TIPS) is an effective treatment for portal hypertension‐related complications. However, careful selection of patients is crucial.

The Prediction of In‐Hospital Mortality in Decompensated Cirrhosis with Acute‐on‐Chronic Liver Failure

Florence Wong, K. Rajender Reddy, Puneeta Tandon, Jennifer C. Lai, Nishita Jagarlamudi, Vanessa Weir, Beverley Kok, Sylvia Kalainy, Yanin T. Srisengfa, Somaya Albhaisi, Bradley Reuter, Chathur Acharya, Jawaid Shaw, Leroy R. Thacker, Jasmohan S. Bajaj – 25 September 2021 – Acute‐on‐chronic liver failure (ACLF) is a condition in cirrhosis associated with organ failure (OF) and high short‐term mortality.

Subscribe to