Psychosocial Assessment Rather Than Severity of Liver Failure Dominates Selection for Liver Transplantation in Patients With Alcohol‐Related Liver Disease

Kimberly E. Daniel, Lindsay A. Matthews, Nimrod Deiss‐Yehiely, Jaime Myers, Maureen Garvey, John P. Rice, Jens Eickhoff, Michael R. Lucey – 30 September 2021 – The Stanford Integrated Psychosocial Assessment for Transplant (SIPAT) is a validated interview tool to assess psychosocial well‐being in candidates for solid organ transplants, with higher scores indicating greater vulnerability.

LiverLearning®: 2021 Webinar: Promoting Equity, Diversity and Inclusion in Communication Near the End of Life

The purpose of this webinar is to present strategies to approach patient and family communication near the end-of-life in the setting of advanced liver disease with a focus on issues related to equity, diversity and inclusion. Patients with advanced liver disease experience high symptom burden, emotional distress, and prognostic uncertainty which makes them particularly vulnerable to suboptimal end-of-life care.

Acute Graft‐Versus‐Host Disease After Orthotopic Liver Transplantation: Predicting This Rare Complication Using Machine Learning

Jason P. Cooper, James D. Perkins, Paul R. Warner, Alexandra Shingina, Scott W. Biggins, Janis L. Abkowitz, Jorge D. Reyes – 28 September 2021 – Acute graft‐versus‐host disease (GVHD) is a rare complication after orthotopic liver transplantation (OLT) that carries high mortality. We hypothesized that machine‐learning algorithms to predict rare events would identify patients at high risk for developing GVHD.

The zinc finger and BTB domain containing protein ZBTB20 regulates plasma triglyceride metabolism by repressing lipoprotein lipase gene transcription in hepatocytes

Hao Li, Gan Liu, Xiaoqing Wan, Luting Zhou, Zhen‐Bang Qin, Xian‐Hua Ma, Kai Su, Ya‐Jin Liu, Jinghao Yuan, Chun‐Chun Wei, An‐Jing Ren, Yu‐Xia Chen, Stephen G. Young, Hai Zhang, Zhifang Xie, Weiping J. Zhang – 27 September 2021

Activation of p53 After Irradiation Impairs the Regenerative Capacity of the Mouse Liver

Makiko Urabe, Hayato Hikita, Yoshinobu Saito, Shinnosuke Kudo, Kenji Fukumoto, Naoki Mizutani, Yuta Myojin, Akira Doi, Katsuhiko Sato, Sadatsugu Sakane, Yuki Makino, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara – 27 September 2021 – Radiation therapy is one of the treatment methods for hepatocellular carcinoma. However, radiation tolerance of the liver is low, and the detailed effect of radiation on liver regeneration has not been clarified.

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