Ductular reaction promotes intrahepatic angiogenesis through Slit2–Roundabout 1 signaling

Mar Coll, Silvia Ariño, Celia Martínez‐Sánchez, Ester Garcia‐Pras, Javier Gallego, Anna Moles, Beatriz Aguilar‐Bravo, Delia Blaya, Julia Vallverdú, Teresa Rubio‐Tomás, Juan Jose Lozano, Elisa Pose, Isabel Graupera, Andrea Fernández‐Vidal, Albert Pol, Ramón Bataller, Jian‐Guo Geng, Pere Ginès, Mercedes Fernandez, Pau Sancho‐Bru – 6 September 2021

Impact of the Kasai Procedure and the Length of Native Liver Survival Time on Outcomes of Liver Transplantation for Biliary Atresia

Liwei Liu, Lin Wei, Wei Qu, Ying Liu, Zhigui Zeng, Haiming Zhang, Min Li, Jimin Liu, Hanlin L. Wang, Kexin Li, Yafei He, Jidong Jia, Liying Sun, Xinyan Zhao, Zhijun Zhu – 4 September 2021 – The aim is to explore the impact of the Kasai procedure (KP) and the length of native liver survival time (NLST) on outcomes of liver transplantation (LT). Patients with biliary atresia (BA), who underwent LT in Beijing Friendship Hospital from January 2017 to December 2019, were enrolled and divided into non‐KP (N‐KP) and post‐KP (P‐KP) groups.

A 3‐Decade, Single‐Center Experience of Liver Transplantation for Cholangiocarcinoma: Impact of Era, Tumor Size, Location, and Neoadjuvant Therapy

Takahiro Ito, James R. Butler, Daisuke Noguchi, Minah Ha, Antony Aziz, Vatche G. Agopian, Joseph DiNorcia, Hasan Yersiz, Douglas G. Farmer, Ronald W. Busuttil, Johnny C. Hong, Fady M. Kaldas – 4 September 2021 – Liver transplantation (LT) for cholangiocarcinoma (CCA) remains limited to a small number of centers. Although the role of neoadjuvant therapy (NAT) has been explored over time, an in‐depth analysis of NAT strategies remains limited. Furthermore, controversy exists regarding acceptable tumor size during patient selection for LT.

The Effect of Acuity Circles on Deceased Donor Transplant and Offer Rates Across Model for End‐Stage Liver Disease Scores and Exception Statuses

Andrew Wey, Samantha Noreen, Sommer Gentry, Matt Cafarella, James Trotter, Nicholas Salkowski, Dorry L. Segev, Ajay Israni, Bertram Kasiske, Ryutaro Hirose, Jon Snyder – 4 September 2021 – Acuity circles (AC), the new liver allocation system, was implemented on February 4, 2020. Difference‐in‐differences analyses estimated the effect of AC on adjusted deceased donor transplant and offer rates across Pediatric End‐Stage Liver Disease (PELD) and Model for End‐Stage Liver Disease (MELD) categories and types of exception statuses.

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