Natural Killer Cells Regulate the Maturation of Liver Sinusoidal Endothelial Cells Thereby Promoting Intrahepatic T‐Cell Responses in a Mouse Model
Yanqin Du, Hu Yan, Shi Zou, Tanvi Khera, Jia Li, Meihong Han, Xiaoli Yang, Baoju Wang, Jia Liu, Shuilin Sun, Xin Zheng, Ulf Dittmer, Mengji Lu, Dongliang Yang, Heiner Wedemeyer, Jun Wu – 4 February 2021 – Functional maturation of liver sinusoidal endothelial cells (LSECs) plays an important role in intrahepatic T‐cell activation and control of viral infections. Natural killer (NK) cells have been reported to prompt the maturation of antigen‐presenting cells (APCs), especially for dendritic cells (DCs), but the interaction between NK cells and LSECs is elusive.