Treatment on the Spleen Prevents the Progression of Secondary Sarcopenia in Patients With Liver Cirrhosis

Masashi Hirooka, Yohei Koizumi, Takaaki Tanaka, Yoshiko Nakamura, Koutarou Sunago, Atsushi Yukimoto, Takao Watanabe, Osamu Yoshida, Teruki Miyake, Yoshio Tokumoto, Bunzo Matsuura, Masanori Abe, Yoichi Hiasa – 31 October 2020 – Hyperammonemia is an important stimulator of myostatin expression, a negative regulator of muscle growth. After splenectomy or partial splenic artery embolization (PSE), hyperammonemia often improves.

Elevated Glycated Hemoglobin Is Associated With Liver Fibrosis, as Assessed by Elastography, in a Population‐Based Study of Mexican Americans

Gordon P. Watt, Isela De La Cerda, Jen‐Jung Pan, Michael B. Fallon, Laura Beretta, Rohit Loomba, Miryoung Lee, Joseph B. McCormick, Susan P. Fisher‐Hoch – 31 October 2020 – Diabetes is associated with liver disease and risk of hepatocellular carcinoma. In this study, we evaluated the association between liver fibrosis measured by transient elastography and four glucose metabolism measures in the Cameron County Hispanic Cohort, a population‐based, randomly selected cohort of Mexican American Hispanics with high rates of diabetes and liver cancer.

Identifying Modifiable Predictors of Long‐Term Survival in Liver Transplant Recipients With Diabetes Mellitus Using Machine Learning

Angeline Yasodhara, Victor Dong, Amirhossein Azhie, Anna Goldenberg, Mamatha Bhat – 28 October 2020 – Diabetes mellitus (DM) significantly impacts long‐term survival after liver transplantation (LT). We identified survival factors for LT recipients who had DM to inform preventive care using machine‐learning analysis. We analyzed risk factors for mortality in patients from across the United States using the Scientific Registry of Transplant Recipients (SRTR). Patients had undergone LT from 1987 to 2019, with a follow‐up of 6.47 years (standard deviation [SD] 5.95).

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