Caroline Ovadia, Alvaro Perdones‐Montero, Konstantina Spagou, Ann Smith, Magali H. Sarafian, Maria Gomez‐Romero, Elena Bellafante, Louise C.D. Clarke, Fouzia Sadiq, Vanya Nikolova, Alice Mitchell, Peter H. Dixon, Natalie Santa‐Pinter, Annika Wahlström, Shadi Abu‐Hayyeh, Julian R.F. Walters, Hanns‐Ulrich Marschall, Elaine Holmes, Julian R. Marchesi, Catherine Williamson – 15 April 2019 – Pregnancy is associated with progressive hypercholanemia, hypercholesterolemia, and hypertriglyceridemia, which can result in metabolic disease in susceptible women.

Chaopeng Li, Tai Rao, Xiaoping Chen, Zhengsheng Zou, Aiwu Wei, Jinfa Tang, Peng Xiong, Pengyan Li, Jing Jing, Tingting He, Zhaofang Bai, Jiye Yin, Zhirong Tan, Peng Yu, Honghao Zhou, Jiabo Wang, Xiaohe Xiao, Dongsheng Ouyang – 15 April 2019 – Polygonum multiflorum (PM) is a well‐known Chinese herbal medicine that has been reported to induce inflammation‐associated idiosyncratic liver injury. This study aimed to identify the genetic basis of susceptibility to PM‐drug‐induced liver injury (PM‐DILI) and to develop biological markers for predicting the risk of PM‐DILI in humans.

Runping Liu, Xiaojiaoyang Li, Weiwei Zhu, Yanyan Wang, Derrick Zhao, Xuan Wang, Emily C. Gurley, Guang Liang, Weidong Chen, Guanhua Lai, William M. Pandak, H. Robert Lippman, Jasmohan S. Bajaj, Phillip B. Hylemon, Huiping Zhou – 15 April 2019 – Activation of hepatic stellate cells (HSCs) represents the primary driving force to promote the progression of chronic cholestatic liver diseases. We previously reported that cholangiocyte‐derived exosomal long noncoding RNA‐H19 (lncRNA‐H19) plays a critical role in promoting cholestatic liver injury.

Hajime Matsushima, Masato Fujiki, Kazunari Sasaki, Daniel M. Rotroff, Mark Sands, Maria Del Pilar Bayona Molano, Federico Aucejo, Teresa Diago Uso, Bijan Eghtesad, Charles Miller, Cristiano Quintini, Koji Hashimoto – 13 April 2019 – The hepatic venous pressure gradient (HVPG) measurement is known to correlate with the severity of portal hypertension in patients with liver cirrhosis.

12 April 2019

Cyriac Abby Philips, Rajaguru Paramaguru, Philip Augustine, Sasidharan Rajesh, Rizwan Ahamed, Tom George, Guruprasad Padsalgi – 12 April 2019 – Drug‐induced liver injury (DILI) due to complementary and alternative medicine (CAM) use is on the rise throughout the world by patients looking for “safer” alternatives. However, data on acute‐on‐chronic liver failure (ACLF) due to CAM are lacking. In a large cohort of patients with cirrhosis, we retrospectively studied CAM‐related health‐seeking behavior and attempted to identify those who developed possible CAM‐DILI‐related ACLF.

Hirsh D. Trivedi, Daryl T.Y. Lau, Tasha B. Kulai, Harmeet Malhi, Robert E. Schwartz, Joseph F. Pisa, Robert S. Brown, Nicholas Russo, Kavitha M. Nair, Giorgio Roccaro, Petra Hirsova, Vikas Gupta, Xu Xu, Tibor Krisko, Enis Kostallari – 12 April 2019

12 April 2019

Min Su You, Woo Hyun Paik, Young Hoon Choi, Bang‐sup Shin, Sang Hyub Lee, Ji Kon Ryu, Yong‐Tae Kim, Kyung‐Suk Suh, Kwang‐Woong Lee, Nam‐Joon Yi, Suk Kyun Hong – 12 April 2019 – Right lobe (RL) living donor liver transplantation (LDLT) usually includes 2 bile duct anastomosis sites, namely, the right anterior and the right posterior segmental ducts. This study aimed to evaluate the optimal treatment for biliary strictures following RL LDLT with respect to unilateral or bilateral drainage techniques.

Hirsh D. Trivedi, Daryl T.Y. Lau, Tasha B. Kulai, Harmeet Malhi, Robert E. Schwartz, Joseph F. Pisa, Robert S. Brown, Nicholas Russo, Kavitha M. Nair, Giorgio Roccaro, Petra Hirsova, Vikas Gupta, Xu Xu, Tibor Krisko, Enis Kostallari – 12 April 2019