Fructose Promotes Leaky Gut, Endotoxemia, and Liver Fibrosis Through Ethanol‐Inducible Cytochrome P450‐2E1–Mediated Oxidative and Nitrative Stress

Young‐Eun Cho, Do‐Kyun Kim, Wonhyo Seo, Bin Gao, Seong‐Ho Yoo, Byoung‐Joon Song – 8 April 2019 – Fructose intake is known to induce obesity, insulin resistance, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD). We aimed to evaluate the effects of fructose drinking on gut leakiness, endotoxemia, and NAFLD and study the underlying mechanisms in rats, mice, and T84 colon cells.

Evaluation of a Multifaceted Intervention to Reduce Health Disparities in Hepatitis C Screening: A Pre‐Post Analysis

Mamta K. Jain, Nicole E. Rich, Chul Ahn, Barbara J. Turner, Joanne M. Sanders, Brian Adamson, Lisa Quirk, Patrice Perryman, Noel O. Santini, Amit G. Singal – 4 April 2019 – Hepatitis C virus (HCV) testing in persons born from 1945 to 1965 has had limited adoption despite guidelines, particularly among racial/ethnic minorities and socioeconomically disadvantaged patients, who have a higher prevalence of disease burden. We examined the effectiveness of a multifaceted intervention to improve HCV screening in a large safety‐net health system.

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