What Are the Optimal Liver Transplantation Criteria for Hepatocellular Carcinoma?
Neil Mehta, Francis Y. Yao – 21 February 2019
Hepatocellular Carcinoma Risk After Direct‐Acting Antiviral Therapy
Feng Su, George N. Ioannou – 21 February 2019
Surveillance and Diagnosis of Hepatocellular Carcinoma
Jane Lim, Amit G. Singal – 21 February 2019
The Spectrum of Hepatic Involvement in Patients With Telomere Disease
Devika Kapuria, Gil Ben‐Yakov, Rebecca Ortolano, Min Ho Cho, Or Kalchiem‐Dekel, Varun Takyar, Shilpa Lingala, Naveen Gara, Michele Tana, Yun Ju Kim, David E. Kleiner, Neal S. Young, Danielle M. Townsley, Christopher Koh, Theo Heller – 21 February 2019 – Loss‐of‐function mutations in genes that encode for components of the telomere repair complex cause accelerated telomere shortening. Hepatic involvement has been recognized as a cause of morbidity in telomere diseases, but very few studies have characterized the nature and extent of liver involvement in affected patients.
The Antiresection Activity of the X Protein Encoded by Hepatitis Virus B
Laifeng Ren, Ming Zeng, Zizhi Tang, Mingyuan Li, Xiaojun Wang, Yang Xu, Yuding Weng, Xiaobo Wang, Huan Wang, Liandi Guo, Bing Zuo, Xin Wang, Si Wang, Jiangyan Lou, Yaxiong Tang, Dezhi Mu, Ning Zheng, Xianhui Wu, Junhong Han, Antony M. Carr, Penelope Jeggo, Cong Liu – 21 February 2019 – Chronic infection of hepatitis B virus (HBV) is associated with an increased incidence of hepatocellular carcinoma (HCC).
Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases
Jorge A. Marrero, Laura M. Kulik, Claude B. Sirlin, Andrew X. Zhu, Richard S. Finn, Michael M. Abecassis, Lewis R. Roberts, Julie K. Heimbach – 21 February 2019
Influence of Type 2 Diabetes Mellitus and Preoperative Hemoglobin A1c Levels on Outcomes of Liver Transplantation
Meagan Gray, Sanjeev Singh, Stephen D. Zucker – 20 February 2019 – Liver transplant centers often establish hemoglobin A1c (HbA1C) criteria for candidates with type 2 diabetes mellitus (T2DM) based on data from other surgical specialties showing worse outcomes in patients with poor glycemic control. However, because of the reduced reliability of HbA1C in cirrhosis, it is unclear whether pretransplant HbA1C values are predictive of postoperative complications in liver recipients.
Serum Metabolomic Profiling Identifies Key Metabolic Signatures Associated With Pathogenesis of Alcoholic Liver Disease in Humans
Zhihong Yang, Praveen Kusumanchi, Ruth A. Ross, Laura Heathers, Kristina Chandler, Adepeju Oshodi, Themis Thoudam, Feng Li, Li Wang, Suthat Liangpunsakul – 20 February 2019 – Alcoholic liver disease (ALD) develops in a subset of heavy drinkers (HDs). The goals of our study were to (1) characterize the global serum metabolomic changes in well‐characterized cohorts of controls (Cs), HDs, and those with alcoholic cirrhosis (AC); (2) identify metabolomic signatures as potential diagnostic markers, and (3) determine the trajectory of serum metabolites in response to alcohol abstinence.