Paola Todesca, Luca Marzi, Rosina Maria Critelli, Biagio Cuffari, Cristian Caporali, Laura Turco, Giovanni Pinelli, Filippo Schepis, Lucia Carulli, Nicola de Maria, Federico Casari, Riccardo Scaglioni, Erica Villa – 25 February 2019
Yang Wang, Nora Kory, Soumik BasuRay, Jonathan C. Cohen, Helen H. Hobbs – 25 February 2019 – A variant (148M) in patatin‐like phospholipase domain‐containing protein 3 (PNPLA3) is a major risk factor for fatty liver disease. Despite its clinical importance, the pathogenic mechanism linking the variant to liver disease remains poorly defined. Previously, we showed that PNPLA3(148M) accumulates to high levels on hepatic lipid droplets (LDs). Here we examined the effect of that accumulation on triglyceride (TG) hydrolysis by adipose triglyceride lipase (ATGL), the major lipase in the liver.
Wen‐Juei Jeng, Yao‐Chun Hsu, Tung‐Hung Su, Chien‐Hung Chen – 22 February 2019
Li‐Ting Cheng, Matthew M. Yeh, Chun‐Chi Lu – 21 February 2019
Alisa Likhitsup, Nataliya Razumilava, Neehar D. Parikh – 21 February 2019
Johann Felden, Amanda J. Craig, Augusto Villanueva – 21 February 2019
Jorge A. Marrero, Laura M. Kulik, Claude B. Sirlin, Andrew X. Zhu, Richard S. Finn, Michael M. Abecassis, Lewis R. Roberts, Julie K. Heimbach – 21 February 2019
Alisa Likhitsup, Nataliya Razumilava, Neehar D. Parikh – 21 February 2019
Jane Lim, Amit G. Singal – 21 February 2019