| AASLD

Aortic Versus Dual Perfusion for Retrieval of the Liver After Brain Death: A National Registry Analysis

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Ahmer M. Hameed, Tony Pang, Peter Yoon, Glenda Balderson, Ronald De Roo, Lawrence Yuen, Vincent Lam, Jerome Laurence, Michael Crawford, Richard D. M. Allen, Wayne J. Hawthorne, Henry C. Pleass – 7 September 2018 – There is lack of consensus in the literature regarding the comparative efficacy of in situ aortic‐only compared with dual (aortic and portal venous) perfusion for retrieval and transplantation of the liver.

Great Expectations: Principal Investigator and Trainee Perspectives on Hiring, Supervision, and Mentoring

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Leonard Kaps, Jonathan G. Stine, Jessica Mellinger, Silvia Vilarinho – 7 September 2018 – A functioning mentor–trainee relationship is of high importance in academia. Discrepancies in expectations between principal investigators (PIs) and trainees are a source of misunderstandings and conflicts, endangering scientific progress and career advancement.

Spotlight on Impactful Research: Increased Risk of Mortality by Fibrosis Stage in Nonalcoholic Fatty Liver Disease: Systemic Review and Meta‐Analysis

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Natasha Roenn – 7 September 2018

Issue Information

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7 September 2018

Pitfalls in Gd‐EOB‐DTPA–Enhanced Liver Magnetic Resonance Imaging With an Emphasis on Nontumorous Lesions

Read more about Pitfalls in Gd‐EOB‐DTPA–Enhanced Liver Magnetic Resonance Imaging With an Emphasis on Nontumorous Lesions

Yedaun Lee, So Yeon Kim, Seung Soo Lee, Seong Ho Park, Kyoung Won Kim, Jae Ho Byun, Moon‐Gyu Lee – 7 September 2018

Closing the Quality Chasm in Cirrhosis

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Kai Rou Tey, Prashanthinie Mohan, Xibei Liu, Archita P. Desai – 7 September 2018

High‐Mobility Group Box‐1 and Liver Disease

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Harriet Gaskell, Xiaodong Ge, Natalia Nieto – 7 September 2018 – High‐mobility group box‐1 (HMGB1) is a ubiquitous protein. While initially thought to be simply an architectural protein due to its DNA‐binding ability, evidence from the last decade suggests that HMGB1 is a key protein participating in the pathogenesis of acute liver injury and chronic liver disease.

PRO: Redistricting of United Network for Organ Sharing Regions to Improve Geographic Disparities in Liver Transplantation

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Fernando H. Calmet, Maria Samuel, Paul Martin – 7 September 2018

Geographic Areas of Liver Distribution in the United States Should Not Be Redesigned According to the 2016 Eight‐District Organ Procurement and Transplantation Network Proposal

Read more about Geographic Areas of Liver Distribution in the United States Should Not Be Redesigned According to the 2016 Eight‐District Organ Procurement and Transplantation Network Proposal

Jennifer Batisti, Emily A. Schonfeld, Clara Tow, Robert S. Brown – 7 September 2018

Dipeptidyl Peptidase‐4 Is a Pro‐Recovery Mediator During Acute Hepatotoxic Damage and Mirrors Severe Shifts in Kupffer Cells

Read more about Dipeptidyl Peptidase‐4 Is a Pro‐Recovery Mediator During Acute Hepatotoxic Damage and Mirrors Severe Shifts in Kupffer Cells

Nádia Duarte, Inês Coelho, Denys Holovanchuk, Joana Inês Almeida, Carlos Penha‐Gonçalves, Maria Paula Macedo – 7 September 2018 – Dipeptidyl peptidase‐4 (DPP‐4 or clusters of differentiation [CD]26) is a multifunctional molecule with established roles in metabolism. Pharmacologic inhibition of DPP‐4 is widely used to improve glycemic control through regulation of the incretin effect. Colaterally, CD26/DPP‐4 inhibition appears to be beneficial in many inflammatory conditions, namely in delaying progression of liver pathology.

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