The middle hepatic vein controversy: Art and science
Chung Mau Lo – 23 July 2018
Old Remedies to Heal the Liver: Novel Effects of Digoxin in Hepatic Sterile Inflammation
Juan P. Arab, Marco Arrese – 23 July 2018
Shunts and bypasses for portal hypertension: Making the right choice
Riccardo Superina – 23 July 2018
Issue Information ‐ Meeting Notices
23 July 2018
Project ECHO: The Specialist Will See You Now
Saira Khaderi, Norman Sussman, Fasiha Kanwal – 23 July 2018
Antiprogrammed Cell Death‐1 Immunotherapy‐Related Secondary Sclerosing Cholangitis
Kohei Ogawa, Kenya Kamimura, Shuji Terai – 23 July 2018
Of Mice and Men and Nonalcoholic Steatohepatitis
David A. Brenner – 23 July 2018
Issue Information
23 July 2018
A Coiled‐Coil Domain Containing 50 Splice Variant Is Modulated by Serine/Arginine‐Rich Splicing Factor 3 and Promotes Hepatocellular Carcinoma in Mice by the Ras Signaling Pathway
Hong Wang, Chris Zhiyi Zhang, Shi‐Xun Lu, Mei‐Fang Zhang, Li‐Li Liu, Rong‐Zhen Luo, Xia Yang, Chun‐Hua Wang, Shi‐Lu Chen, Yang‐Fan He, Dan Xie, Rui‐Hua Xu, Jing‐Ping Yun – 20 July 2018 – Deregulation of alternative splicing contributes to the malignant progression of cancer. Little is known about the significant alternative splicing events in hepatocellular carcinoma (HCC). High‐throughput sequencing revealed that coiled‐coil domain containing 50 (CCDC50) pre‐mRNA is aberrantly spliced in 50% of our HCC cases.