Stefan Wirth, Hongfei Zhang, Winita Hardikar, Kathleen B. Schwarz, Etienne Sokal, Weibo Yang, Huimin Fan, Vyacheslav Morozov, Qing Mao, Hong Deng, Yang Huang, Lei Yang, Nicolas Frey, Clare Nasmyth‐Miller, Vedran Pavlovic, Cynthia Wat – 24 April 2018 – Children with chronic hepatitis B (CHB) represent an area of unmet medical need, attributed to increased lifetime risk of CHB sequelae and limited therapeutic options compared with adult CHB patients. The PEG‐B‐ACTIVE (NCT01519960) phase III study evaluated peginterferon (PegIFN) alfa‐2a treatment in children aged 3 to <18 years with CHB.

Jasmohan S. Bajaj, Richard Moreau, Patrick S Kamath, Hugo E. Vargas, Vicente Arroyo, K. Rajender Reddy, Gyongyi Szabo, Puneeta Tandon, Jody Olson, Constantine Karvellas, Thierry Gustot, Jennifer C. Lai, Florence Wong – 24 April 2018 – Acute on chronic liver failure (ACLF) is the culmination of chronic liver disease and extrahepatic organ failures, which is associated with a high short‐term mortality and immense health care expenditure. There are varying definitions for organ failures and ACLF in Europe, North America, and Asia.

Angela C. Cheung, Aliya F. Gulamhusein, Brian D. Juran, Erik M. Schlicht, Bryan M. McCauley, Mariza de Andrade, Elizabeth J. Atkinson, Konstantinos N. Lazaridis – 24 April 2018 – The United Kingdom‐Primary Biliary Cholangitis (UK‐PBC) risk scores are a set of prognostic models that estimate the risk of end‐stage liver disease in patients with PBC at 5‐, 10‐ and 15‐year intervals. They have not been externally validated outside the United Kingdom.

Jasmohan S. Bajaj, Richard Moreau, Patrick S Kamath, Hugo E. Vargas, Vicente Arroyo, K. Rajender Reddy, Gyongyi Szabo, Puneeta Tandon, Jody Olson, Constantine Karvellas, Thierry Gustot, Jennifer C. Lai, Florence Wong – 24 April 2018 – Acute on chronic liver failure (ACLF) is the culmination of chronic liver disease and extrahepatic organ failures, which is associated with a high short‐term mortality and immense health care expenditure. There are varying definitions for organ failures and ACLF in Europe, North America, and Asia.

John A. Geha, N. Thao Galvan, Michael Kueht, Dor Yoeli, Joe D. Geha, Abbas Rana, Ronald T. Cotton, Christine A. O’Mahony, John A. Goss – 23 April 2018

Gyongyi Szabo – 23 April 2018

23 April 2018

Carlo Pulitano, Phong Ho, Deborah Verran, Charbel Sandroussi, David Joseph, David G. Bowen, Geoffrey W. McCaughan, Michael Crawford, Nicholas Shackel – 23 April 2018 – Acute kidney injury (AKI) after liver transplantation (LT) is a common event, but its pathogenesis remains unclear. The aim of this prospective study is to investigate the potential relationship between postreperfusion gene expression, serum mediators, and the onset of AKI after LT. Sixty‐five consecutive patients undergoing LT were included in the study.

23 April 2018

Cecilia Zazueta, Mabel Buelna‐Chontal, Arturo Macías‐López, Nadia G. Román‐Anguiano, Héctor González‐Pacheco, Natalia Pavón, Rashidi Springall, Alberto Aranda‐Frausto, Rafael Bojalil, Alejandro Silva‐Palacios, Rodrigo Velázquez‐Espejel, Sonia Galvan Arzate, Francisco Correa – 20 April 2018 – Cytidine‐5'‐diphosphocholine (CDP‐choline) participates as an intermediary in the synthesis of phosphatidylcholine, an essential component of cellular membranes.