Neutrophil extracellular traps promote inflammation and development of hepatocellular carcinoma in nonalcoholic steatohepatitis

Dirk J. van der Windt, Vikas Sud, Hongji Zhang, Patrick R. Varley, Julie Goswami, Hamza O. Yazdani, Samer Tohme, Patricia Loughran, Robert M. O'Doherty, Marta I. Minervini, Hai Huang, Richard L. Simmons, Allan Tsung – 6 April 2018 – Nonalcoholic steatohepatitis (NASH) is a progressive, inflammatory form of fatty liver disease. It is the most rapidly rising risk factor for the development of hepatocellular carcinoma (HCC), which can arise in NASH with or without cirrhosis. The inflammatory signals promoting the progression of NASH to HCC remain largely unknown.

Elbasvir/grazoprevir in Asia‐Pacific/Russian participants with chronic hepatitis C virus genotype 1, 4, or 6 infection

Jacob George, Eduard Burnevich, I‐Shyan Sheen, Jeong Heo, Nguyen Van Kinh, Tawesak Tanwandee, Pin‐Nan Cheng, Do Young Kim, Won Young Tak, Svetlana Kizhlo, Konstantin Zhdanov, Vasily Isakov, Liwen Liang, Pauline Lindore, Joy Ginanni, Bach‐Yen Nguyen, Janice Wahl, Eliav Barr, Michael Robertson, Paul Ingravallo, Rohit Talwani, on behalf of the C‐CORAL Study Investigators – 4 April 2018 – The prevalence of hepatitis C virus (HCV) infection in Asian countries is high.

Elbasvir/grazoprevir in Asia‐Pacific/Russian participants with chronic hepatitis C virus genotype 1, 4, or 6 infection

Jacob George, Eduard Burnevich, I‐Shyan Sheen, Jeong Heo, Nguyen Van Kinh, Tawesak Tanwandee, Pin‐Nan Cheng, Do Young Kim, Won Young Tak, Svetlana Kizhlo, Konstantin Zhdanov, Vasily Isakov, Liwen Liang, Pauline Lindore, Joy Ginanni, Bach‐Yen Nguyen, Janice Wahl, Eliav Barr, Michael Robertson, Paul Ingravallo, Rohit Talwani, on behalf of the C‐CORAL Study Investigators – 4 April 2018 – The prevalence of hepatitis C virus (HCV) infection in Asian countries is high.

Biliary Atresia: Clinical and Research Challenges for the Twenty‐First Century

Jorge A. Bezerra, Rebecca G. Wells, Cara L. Mack, Saul J. Karpen, Jay H. Hoofnagle, Edward Doo, Ronald J. Sokol – 31 March 2018 – Biliary atresia (BA) is a fibroinflammatory disease of the intrahepatic and extrahepatic biliary tree. Surgical hepatic portoenterostomy (HPE) may restore bile drainage, but progression of the intrahepatic disease results in complications of portal hypertension and advanced cirrhosis in most children.

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