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Guo‐Feng Chen, Cheng Wang, George Lau – 28 October 2017
Can negligible hepatic steatosis determined by magnetic resonance imaging–proton density fat fraction obviate the need for liver biopsy in potential liver donors?
Janakan Satkunasingham, Hooman Hosseini Nik, Sandra Fischer, Ravi Menezes, Nazia Selzner, Mark Cattral, David Grant, Kartik Jhaveri – 28 October 2017 – The purpose of this study is to determine whether magnetic resonance (MR)–proton density fat fraction (PDFF) estimate of negligible hepatic fat percentage (<5%) can exclude significant hepatic steatosis (≥10%) in living liver donor candidates obviating the need for liver biopsy and to perform intraindividual comparisons between MR‐PDFF techniques for hepatic steatosis quantification.
The role of molecular adsorbent recirculating system in pediatric acute liver failure
Jesús Quintero Bernabeu, Juan Ortega López, Javier Juampérez Goñi, Ecaterina Julio Tatis, Maria Mercadal‐Hally, Itxarone Bilbao Aguirre, Carlos Rodrigo Gonzalo de Liria, Ramon Charco Torra – 28 October 2017
Hydrodynamics of bile flow: Lessons from computational modeling
Peter L.M. Jansen – 27 October 2017
Hepatocyte DUSP14 maintains metabolic homeostasis and suppresses inflammation in the liver
Siyuan Wang, Zhen‐Zhen Yan, Xia Yang, Shimin An, Kuo Zhang, Yu Qi, Jilin Zheng, Yan‐Xiao Ji, Pi‐Xiao Wang, Chun Fang, Xue‐Yong Zhu, Li‐Jun Shen, Feng‐Juan Yan, Rong Bao, Song Tian, Zhi‐Gang She, Yi‐Da Tang – 27 October 2017 – Nonalcoholic fatty liver disease (NAFLD) is a prevalent and complex disease that confers a high risk of severe liver disorders. Despite such public and clinical health importance, very few effective therapies are currently available for NAFLD.
Pro (With Caution): Extended oncologic indications in liver transplantation
Vincenzo Mazzaferro, Carlo Battiston, Carlo Sposito – 27 October 2017 – The success of liver transplantation (LT) in curing cancer (particularly hepatocellular carcinoma and hepatic metastases from neuroendocrine tumors) is based on the augmented oncologic potentials of the total hepatectomy and on restrictive criteria applied to patient selection. Consensus on the grade of expansion of conventional limits and implementation of alternative indications to LT (cholangiocarcinoma and metastases from colorectal cancer) has not been reached.
Can smart nanomedicine deliver effective targeted cytotoxic treatments to hepatocellular carcinomas while reducing the liver damage?
Shuichi Aoki, Mark Cobbold, Andrew X. Zhu, Dan G. Duda – 27 October 2017
Pregnancy in Wilson disease
Atoosa Rabiee, James P.A. Hamilton – 27 October 2017
Nutrition and the transplant candidate
Vera C. Mazurak, Puneeta Tandon, Aldo J. Montano‐Loza – 26 October 2017 – Cirrhosis is the most common indication for liver transplantation (LT) worldwide. Malnutrition is present in at least two‐thirds of patients with cirrhosis awaiting LT. It negatively impacts survival, quality of life, and the ability to respond to stressors, such as infection and surgery. Muscle wasting or sarcopenia is the most objective feature of chronic protein malnutrition in cirrhosis, and this condition is associated with increased morbidity and mortality before and after LT.