Argininosuccinate synthase 1 (ASS1): A marker of unclassified hepatocellular adenoma and high bleeding risk
Elodie Henriet, Aya Abou Hammoud, Jean‐William Dupuy, Benjamin Dartigues, Zakaria Ezzoukry, Nathalie Dugot‐Senant, Thierry Leste‐Lasserre, Nestor Pallares‐Lupon, Macha Nikolski, Brigitte Le Bail, Jean‐Frédéric Blanc, Charles Balabaud, Paulette Bioulac‐Sage, Anne‐Aurélie Raymond, Frédéric Saltel – 23 June 2017 – Hepatocellular adenomas (HCAs) are rare benign tumors divided into three main subgroups defined by pathomolecular features, HNF1A (H‐HCA), mutated β‐catenin (b‐HCA), and inflammatory (IHCA).
Healthy controls in nonalcoholic fatty liver disease management: A biomedical research perspective
Saumya Pandey – 23 June 2017
Alcohol abstinence in patients surviving an episode of alcoholic hepatitis: Prediction and impact on long‐term survival
José Altamirano, Hugo López‐Pelayo, Javier Michelena, Patricia D. Jones, Lluisa Ortega, Pere Ginès, Juan Caballería, Antoni Gual, Ramón Bataller, Anna Lligoña – 23 June 2017 – Alcoholic hepatitis (AH) is the most severe form of alcoholic liver disease. Most studies have focused on short‐term prognosis, whereas factors associated with long‐term survival are largely unknown.
Masthead
22 June 2017
A liver‐specific gene expression panel predicts the differentiation status of in vitro hepatocyte models
Dae‐Soo Kim, Jea‐Woon Ryu, Mi‐Young Son, Jung‐Hwa Oh, Kyung‐Sook Chung, Sugi Lee, Jeong‐Ju Lee, Jun‐Ho Ahn, Ju‐Sik Min, Jiwon Ahn, Hyun Mi Kang, Janghwan Kim, Cho‐Rok Jung, Nam‐Soon Kim, Hyun‐Soo Cho – 22 June 2017 – Alternative cell sources, such as three‐dimensional organoids and induced pluripotent stem cell–derived cells, might provide a potentially effective approach for both drug development applications and clinical transplantation.
Notices
22 June 2017
The emergence of NS5B resistance associated substitution S282T after sofosbuvir‐based treatment
Edward J. Gane, Sophie Metivier, Ronald Nahass, Michael Ryan, Catherine A. Stedman, Evguenia S. Svarovskaia, Hongmei Mo, Brian Doehle, Hadas Dvory‐Sobol, Charlotte Hedskog, Ming Lin, Diana M. Brainard, Jenny C. Yang, John G. McHutchison, Mark Sulkowski, Ziad Younes, Eric Lawitz – 22 June 2017 – S282T in NS5B is the primary amino acid substitution associated with resistance to sofosbuvir (SOF) but has rarely been detected in patients treated with a SOF‐based regimen.