Neutrophil‐to‐lymphocyte ratio correlates with proinflammatory neutrophils and predicts death in low model for end‐stage liver disease patients with cirrhosis
Avash Kalra, Joel P. Wedd, Kiran M. Bambha, Jane Gralla, Lucy Golden‐Mason, Christine Collins, Hugo R. Rosen, Scott W. Biggins – 22 December 2016 – The Model for End‐Stage Liver Disease (MELD) score has reduced accuracy for liver transplantation (LT) wait‐list mortality when MELD ≤ 20. Neutrophil‐to‐lymphocyte ratio (NLR) is a biomarker associated with systemic inflammation and may predict cirrhotic decompensation and death. We aimed to evaluate the prognostic utility of high NLR (≥4) for liver‐related death among low MELD patients listed for LT, controlling for stage of cirrhosis.