21 December 2016

21 December 2016

Ahmad H. Ali, James H. Tabibian, Keith D. Lindor – 21 December 2016 – Cholestatic liver diseases are conditions with impaired bile formation and/or flow due to genetic, immunologic, environmental, or other causes. Unless successfully treated, this can lead to chronic liver injury and end‐stage liver disease. Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) embody the most prominent adult cholestatic liver diseases with regard to incidence, morbidity, and mortality.

William F. Balistreri, Karen F. Murray, Philip Rosenthal, Sanjay Bansal, Chuan‐Hao Lin, Kathryn Kersey, Benedetta Massetto, Yanni Zhu, Bittoo Kanwar, Polina German, Evguenia Svarovskaia, Diana M. Brainard, Jessica Wen, Regino P. Gonzalez‐Peralta, Maureen M. Jonas, Kathleen Schwarz – 20 December 2016 – No all‐oral, direct‐acting antiviral regimens have been approved for children with chronic hepatitis C virus (HCV) infection.

George K. Michalopoulos – 20 December 2016 – In contrast to all other organs, liver‐to‐body‐weight ratio needs to be maintained always at 100% of what is required for body homeostasis. Adjustment of liver size to 100% of what is required for homeostasis has been called “hepatostat.” Removal of a portion of any other organ is followed with local regeneration of a limited degree, but it never attempts to reach 100% of the original size. The complex mechanisms involved in this uniquely hepatic process encompass a variety of regenerative pathways that are specific to different types of injury.

Zongxin Ling, Xia Liu, Yiwen Cheng, Li Shao, Haiyin Jiang, Lanjuan Li – 20 December 2016

Annalisa Berzigotti, Agustín Albillos, Candid Villanueva, Joan Genescá, Alba Ardevol, Salvador Augustín, Jose Luis Calleja, Rafael Bañares, Juan Carlos García‐Pagán, Francisco Mesonero, Jaime Bosch, on behalf of the Ciberehd SportDiet Collaborative Group – 20 December 2016 – Obesity increases the risk of clinical decompensation in cirrhosis, possibly by increasing portal pressure.

Laurent Savale, Caroline Sattler, Audrey Coilly, Filoména Conti, Sébastien Renard, Claire Francoz, Hélène Bouvaist, Cyrille Feray, Patrick Borentain, Xavier Jaïs, David Montani, Florence Parent, Caroline O'Connell, Philippe Hervé, Marc Humbert, Gérald Simonneau, Didier Samuel, Yvon Calmus, Christophe Duvoux, François Durand, Jean Charles Duclos‐Vallée, Olivier Sitbon – 20 December 2016 – Portopulmonary hypertension (PoPH) is diagnosed in 2‐6% of liver transplantation (LT) candidates. We studied outcomes of candidates for LT suffering from PoPH.

Rahul Gupta, Jyoti Gupta – 20 December 2016

Benjamin Lelouvier, Florence Servant, Michael Courtney, Rémy Burcelin, Jacques Amar – 20 December 2016